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• W2044932005 abstract "In this work, we investigated the role of four independent process parameters, namely product temperature at the heat exchanger outlet, mean residence time, temperature increase between the heat exchanger inlet and outlet, and heat effectiveness, in the protein denaturation, aggregation, and fouling of a β-lactoglobulin (β-lg) concentrate that was chosen as model fluid for milk derivatives. A pilot-scale plate heat exchanger in countercurrent configuration, supplied with a holder, was used in order to mimic industrial process conditions. The denaturation level and aggregates size of the heat treated β-lg concentrate at the exchanger and holder outlets, along with the fouling mass in the plate heat exchanger were simultaneously determined. The results indicated that β-lg denaturation, aggregation, and fouling reactions were mainly governed by the temperature profile in the investigated range of operating conditions, even though a small influence of residence time and heating rate was highlighted in the less denaturing conditions. A dimensional analysis was performed to identify the key dimensionless numbers governing β-lg denaturation, aggregation, and fouling mechanisms in the heat treatment of a β-lg concentrate. This allowed to emphasise the major influence of the Arrhenius exponential factor of β-lg unfolding reaction, both related to temperature and β-lg reactivity. The first Damköhler and Reynolds numbers, related to residence time and hydrodynamic conditions in the heat exchanger, as well as the heat exchange process parameters, linked to the heat effectiveness and the bulk-wall temperature differences, had also a small impact on β-lg chemical behaviour. Moreover, empirical relationships based only on the Arrhenius exponential factor of β-lg unfolding reaction permitted to describe the main trends observed in denaturation levels, aggregate sizes, and fouling masses, which underlined the predominant role of temperature and β-lg reactivity in the investigated operating conditions. This study outlines finally that fast heat treatments permit to minimise fouling issues." @default.
• W2044932005 created "2016-06-24" @default.
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• W2044932005 date "2013-09-01" @default.
• W2044932005 modified "2023-09-24" @default.
• W2044932005 title "β-lactoglobulin denaturation, aggregation, and fouling in a plate heat exchanger: Pilot-scale experiments and dimensional analysis" @default.
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• W2044932005 doi "https://doi.org/10.1016/j.ces.2013.06.045" @default.
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