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- W2044977356 abstract "Germ-free mice were maintained on polysaccharide-rich or simple-sugar diets and colonized for 10 days with an organism also found in human guts, Bacteroides thetaiotaomicron , followed by whole-genome transcriptional profiling of bacteria and mass spectrometry of cecal glycans. We found that these bacteria assembled on food particles and mucus, selectively induced outer-membrane polysaccharide-binding proteins and glycoside hydrolases, prioritized the consumption of liberated hexose sugars, and revealed a capacity to turn to host mucus glycans when polysaccharides were absent from the diet. This flexible foraging behavior should contribute to ecosystem stability and functional diversity." @default.
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- W2044977356 date "2005-03-25" @default.
- W2044977356 modified "2023-10-10" @default.
- W2044977356 title "Glycan Foraging in Vivo by an Intestine-Adapted Bacterial Symbiont" @default.
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- W2044977356 doi "https://doi.org/10.1126/science.1109051" @default.
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