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• W2044988204 abstract "Deep biochemical and cellular similarities exist between Drosophila and vertebrates in the development and function of all organs. Despite their morphological differences, it is considered ever more likely that the hearing sensory cells have a common evolutionary origin and that consequently the molecular mechanisms that govern their functions are at least partially conserved. Thanks to transgenesis techniques and to the rich collection of mutant stocks well characterized from genetic, molecular and physiological points of view, Drosophila provides the means to test in vivo vertebrate gene functions in known metabolic and cellular pathways. In addition, the search for sequence homologies between human and Drosophila genes has allowed the identification of many disease genes in the human auditory system. These results indicate that Drosophila is a good model for the study of the genes that cause deafness in humans, and offers the possibility of using the numerous and sophisticated genetic tools of the inse..." @default.
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• W2044988204 date "2012-05-08" @default.
• W2044988204 modified "2023-09-25" @default.
• W2044988204 title "The sound and the fly:Drosophilain biomedical research on human hearing" @default.
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• W2044988204 doi "https://doi.org/10.3109/1651386x.2012.685222" @default.
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