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- W2044995188 abstract "Inflammation muqueuse et altération de l'épithélium bronchique sont deux composantes physiopathologiques importantes dans l'asthme. Les relations entre ces deux événements sont encore mal connues. La description récente de lésions de fibrose sous la membrane basale de l'épithélium bronchique, dans cette maladie, nous a incité à envisager cette fibrose comme une véritable tentative de cicatrisation du processus inflammatoire, lui-même induit par l'agression épithéliale. Une réflexion sur les mécanismes immunobiochimiques capables d'orchestrer ces différentes étapes de l'inflammation est proposée dans cette revue générale. Mucosal inflammation and damage to the bronchial epithelium are two important pathophysiological components in asthma. The links between these two events remain poorly understood. The recent description of fibrosis lesions under the basal membrane of the bronchial epithelium in this disease led us to envisage such fibrosis as a true attempt at healing of the inflammatory process, itself induced by epithelial aggression. This general review contains thoughts regarding the immunobiochemical mechanisms capable of orchestrating these different stages of inflammation." @default.
- W2044995188 created "2016-06-24" @default.
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- W2044995188 date "1991-01-01" @default.
- W2044995188 modified "2023-09-26" @default.
- W2044995188 title "L'altération bronchique dans l'asthme : de l'inflammation à la cicatrisation" @default.
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- W2044995188 doi "https://doi.org/10.1016/s0335-7457(05)80300-4" @default.
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