FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045001074> ?p ?o ?g. }

• W2045001074 endingPage "196" @default.
• W2045001074 startingPage "196" @default.
• W2045001074 abstract "To test whether intra-articular injection of porcine adipose-derived stem cells (ADSCs) can treat canine osteoarthritis (OA).To enroll in this study dogs must have stifle joint OA that had lasted ≥ 3 mo and been treated with OA medication without significant improvement. Three dogs fulfilled these criteria and were thus subjects for ADSCs treatment. ADSCs were isolated from abdominal adipose tissue of a 2-mo-old female Yorkshire pig. Their stem cell marker expression was examined by immunofluorescence staining. For treatment, 5 million ADSCs were injected into the diseased joint of each dog. In the next 48 h, the patient was observed for signs of inflammatory and allergic reactions. The patient was then discharged to the owner and, at 2, 6, and 12 wk, followed up with orthopedic assessment, owner questionnaire, X-ray imaging, and force-plate gait analysis.Porcine ADSCs expressed mesenchymal stem cell markers CD90 and CD105. Injection of porcine ADSCs into canine stifle joints did not cause any inflammatory or allergic reactions. Orthopedic evaluation found improvements in two dogs, particularly at the longest time point. Owners' evaluation found increased capacity and decreased pain in all three dogs' activities such as walking and running. Radiographic evaluation did not find statistically significant differences before and after treatment. Force-plate analysis found significant improvements in all three dogs after treatment.Xenotransplantation of ADSCs for the treatment of OA is feasible. Further studies are needed to validate this novel treatment modality, which can then be implemented for the routine treatment of OA in veterinary medicine." @default.
• W2045001074 created "2016-06-24" @default.
• W2045001074 creator A5036873753 @default.
• W2045001074 creator A5060075363 @default.
• W2045001074 creator A5075195826 @default.
• W2045001074 creator A5086863834 @default.
• W2045001074 creator A5091637974 @default.
• W2045001074 date "2014-01-01" @default.
• W2045001074 modified "2023-10-11" @default.
• W2045001074 title "Intra-articular transplantation of porcine adipose-derived stem cells for the treatment of canine osteoarthritis: A pilot study" @default.
• W2045001074 cites W119303876 @default.
• W2045001074 cites W126085740 @default.
• W2045001074 cites W1806253550 @default.
• W2045001074 cites W1965727192 @default.
• W2045001074 cites W1967618429 @default.
• W2045001074 cites W1974198316 @default.
• W2045001074 cites W1977439519 @default.
• W2045001074 cites W1986147205 @default.
• W2045001074 cites W1990954463 @default.
• W2045001074 cites W1996353134 @default.
• W2045001074 cites W2015050458 @default.
• W2045001074 cites W2017256180 @default.
• W2045001074 cites W2026123588 @default.
• W2045001074 cites W2029927816 @default.
• W2045001074 cites W2030594039 @default.
• W2045001074 cites W2038022281 @default.
• W2045001074 cites W2038773696 @default.
• W2045001074 cites W2058753306 @default.
• W2045001074 cites W2082144896 @default.
• W2045001074 cites W2100905713 @default.
• W2045001074 cites W2117042362 @default.
• W2045001074 cites W2150683839 @default.
• W2045001074 cites W2155044423 @default.
• W2045001074 doi "https://doi.org/10.5500/wjt.v4.i3.196" @default.
• W2045001074 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4208083" @default.
• W2045001074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25346893" @default.
• W2045001074 hasPublicationYear "2014" @default.
• W2045001074 type Work @default.
• W2045001074 sameAs 2045001074 @default.
• W2045001074 citedByCount "30" @default.
• W2045001074 countsByYear W20450010742015 @default.
• W2045001074 countsByYear W20450010742016 @default.
• W2045001074 countsByYear W20450010742017 @default.
• W2045001074 countsByYear W20450010742018 @default.
• W2045001074 countsByYear W20450010742019 @default.
• W2045001074 countsByYear W20450010742020 @default.
• W2045001074 countsByYear W20450010742021 @default.
• W2045001074 countsByYear W20450010742022 @default.
• W2045001074 countsByYear W20450010742023 @default.
• W2045001074 crossrefType "journal-article" @default.
• W2045001074 hasAuthorship W2045001074A5036873753 @default.
• W2045001074 hasAuthorship W2045001074A5060075363 @default.
• W2045001074 hasAuthorship W2045001074A5075195826 @default.
• W2045001074 hasAuthorship W2045001074A5086863834 @default.
• W2045001074 hasAuthorship W2045001074A5091637974 @default.
• W2045001074 hasBestOaLocation W20450010741 @default.
• W2045001074 hasConcept C10205521 @default.
• W2045001074 hasConcept C116716535 @default.
• W2045001074 hasConcept C126322002 @default.
• W2045001074 hasConcept C141071460 @default.
• W2045001074 hasConcept C142724271 @default.
• W2045001074 hasConcept C171089720 @default.
• W2045001074 hasConcept C198826908 @default.
• W2045001074 hasConcept C204787440 @default.
• W2045001074 hasConcept C2776164576 @default.
• W2045001074 hasConcept C2776626428 @default.
• W2045001074 hasConcept C2778434673 @default.
• W2045001074 hasConcept C2778442404 @default.
• W2045001074 hasConcept C2779699715 @default.
• W2045001074 hasConcept C2779771469 @default.
• W2045001074 hasConcept C28328180 @default.
• W2045001074 hasConcept C2911091166 @default.
• W2045001074 hasConcept C54355233 @default.
• W2045001074 hasConcept C68312169 @default.
• W2045001074 hasConcept C71924100 @default.
• W2045001074 hasConcept C86803240 @default.
• W2045001074 hasConceptScore W2045001074C10205521 @default.
• W2045001074 hasConceptScore W2045001074C116716535 @default.
• W2045001074 hasConceptScore W2045001074C126322002 @default.
• W2045001074 hasConceptScore W2045001074C141071460 @default.
• W2045001074 hasConceptScore W2045001074C142724271 @default.
• W2045001074 hasConceptScore W2045001074C171089720 @default.
• W2045001074 hasConceptScore W2045001074C198826908 @default.
• W2045001074 hasConceptScore W2045001074C204787440 @default.
• W2045001074 hasConceptScore W2045001074C2776164576 @default.
• W2045001074 hasConceptScore W2045001074C2776626428 @default.
• W2045001074 hasConceptScore W2045001074C2778434673 @default.
• W2045001074 hasConceptScore W2045001074C2778442404 @default.
• W2045001074 hasConceptScore W2045001074C2779699715 @default.
• W2045001074 hasConceptScore W2045001074C2779771469 @default.
• W2045001074 hasConceptScore W2045001074C28328180 @default.
• W2045001074 hasConceptScore W2045001074C2911091166 @default.
• W2045001074 hasConceptScore W2045001074C54355233 @default.
• W2045001074 hasConceptScore W2045001074C68312169 @default.
• W2045001074 hasConceptScore W2045001074C71924100 @default.
• W2045001074 hasConceptScore W2045001074C86803240 @default.
• W2045001074 hasIssue "3" @default.
• W2045001074 hasLocation W20450010741 @default.

• next