Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045005503> ?p ?o ?g. }
- W2045005503 endingPage "380" @default.
- W2045005503 startingPage "366" @default.
- W2045005503 abstract "Although chondroitin sulfate proteoglycans (CSPGs) are major components of the embryonic extracellular matrix, little attention has been paid to specific CSPGs in early heart development, in part because appropriate antibodies were not available. Therefore we prepared specific polyclonal antibodies against chicken aggrecan, versican, neurocan, and phosphacan. Western blotting and immunohistochemical studies revealed the presence of aggrecan and versican in stages 12-21 chicken embryo hearts in distinctive spatial and temporal patterns. Because this is the first demonstration of aggrecan in heart tissue, we further used RT-PCR to confirm that aggrecan is expressed in the heart and in situ hybridization to confirm the pattern of expression determined using antibodies. Versican is found in the myocardium and the myocardial basement membrane. In contrast, aggrecan is specifically colocalized with several groups of migrating cells including endocardial cushion tissue cells, epicardial cells, a mesenchymal cell population in the outflow tract that may be of neural crest origin, and a mesenchymal cell population in the inflow tract. The combined observations indicate that versican and aggrecan are expressed in unique patterns and suggest that they play very different roles in development." @default.
- W2045005503 created "2016-06-24" @default.
- W2045005503 creator A5011998205 @default.
- W2045005503 creator A5017447077 @default.
- W2045005503 creator A5018335979 @default.
- W2045005503 creator A5038146016 @default.
- W2045005503 creator A5045884114 @default.
- W2045005503 creator A5075682333 @default.
- W2045005503 date "1999-12-01" @default.
- W2045005503 modified "2023-10-09" @default.
- W2045005503 title "Distinct spatial and temporal distributions of aggrecan and versican in the embryonic chick heart" @default.
- W2045005503 cites W1481596686 @default.
- W2045005503 cites W1484703368 @default.
- W2045005503 cites W1510794293 @default.
- W2045005503 cites W1521949639 @default.
- W2045005503 cites W1531779321 @default.
- W2045005503 cites W1571924012 @default.
- W2045005503 cites W1574987094 @default.
- W2045005503 cites W1575127176 @default.
- W2045005503 cites W1598171890 @default.
- W2045005503 cites W1605448867 @default.
- W2045005503 cites W1903208355 @default.
- W2045005503 cites W1966960873 @default.
- W2045005503 cites W1971156818 @default.
- W2045005503 cites W1973596817 @default.
- W2045005503 cites W1974477641 @default.
- W2045005503 cites W1978514720 @default.
- W2045005503 cites W1984545951 @default.
- W2045005503 cites W1992142018 @default.
- W2045005503 cites W1995869857 @default.
- W2045005503 cites W2008632495 @default.
- W2045005503 cites W2009759006 @default.
- W2045005503 cites W2010709317 @default.
- W2045005503 cites W2022892939 @default.
- W2045005503 cites W2026126125 @default.
- W2045005503 cites W2029340713 @default.
- W2045005503 cites W2034163119 @default.
- W2045005503 cites W2035306678 @default.
- W2045005503 cites W2038429210 @default.
- W2045005503 cites W2047987857 @default.
- W2045005503 cites W2053679827 @default.
- W2045005503 cites W2056466097 @default.
- W2045005503 cites W2058797108 @default.
- W2045005503 cites W2062106375 @default.
- W2045005503 cites W2065530558 @default.
- W2045005503 cites W2068292119 @default.
- W2045005503 cites W2069940171 @default.
- W2045005503 cites W2075346359 @default.
- W2045005503 cites W2084492934 @default.
- W2045005503 cites W2095741501 @default.
- W2045005503 cites W2101435003 @default.
- W2045005503 cites W2111064007 @default.
- W2045005503 cites W2114545874 @default.
- W2045005503 cites W2119609292 @default.
- W2045005503 cites W2126732550 @default.
- W2045005503 cites W2128184552 @default.
- W2045005503 cites W2150060856 @default.
- W2045005503 cites W2154741774 @default.
- W2045005503 cites W2168876033 @default.
- W2045005503 cites W2170326305 @default.
- W2045005503 cites W2466013791 @default.
- W2045005503 doi "https://doi.org/10.1002/(sici)1097-0185(19991201)256:4<366::aid-ar4>3.0.co;2-#" @default.
- W2045005503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10589023" @default.
- W2045005503 hasPublicationYear "1999" @default.
- W2045005503 type Work @default.
- W2045005503 sameAs 2045005503 @default.
- W2045005503 citedByCount "11" @default.
- W2045005503 countsByYear W20450055032012 @default.
- W2045005503 countsByYear W20450055032013 @default.
- W2045005503 countsByYear W20450055032015 @default.
- W2045005503 countsByYear W20450055032018 @default.
- W2045005503 crossrefType "journal-article" @default.
- W2045005503 hasAuthorship W2045005503A5011998205 @default.
- W2045005503 hasAuthorship W2045005503A5017447077 @default.
- W2045005503 hasAuthorship W2045005503A5018335979 @default.
- W2045005503 hasAuthorship W2045005503A5038146016 @default.
- W2045005503 hasAuthorship W2045005503A5045884114 @default.
- W2045005503 hasAuthorship W2045005503A5075682333 @default.
- W2045005503 hasConcept C104317684 @default.
- W2045005503 hasConcept C105702510 @default.
- W2045005503 hasConcept C142724271 @default.
- W2045005503 hasConcept C145103041 @default.
- W2045005503 hasConcept C159470946 @default.
- W2045005503 hasConcept C197534660 @default.
- W2045005503 hasConcept C204787440 @default.
- W2045005503 hasConcept C2776164576 @default.
- W2045005503 hasConcept C2779335624 @default.
- W2045005503 hasConcept C2780550940 @default.
- W2045005503 hasConcept C3020332539 @default.
- W2045005503 hasConcept C54355233 @default.
- W2045005503 hasConcept C71924100 @default.
- W2045005503 hasConcept C86803240 @default.
- W2045005503 hasConceptScore W2045005503C104317684 @default.
- W2045005503 hasConceptScore W2045005503C105702510 @default.
- W2045005503 hasConceptScore W2045005503C142724271 @default.
- W2045005503 hasConceptScore W2045005503C145103041 @default.
- W2045005503 hasConceptScore W2045005503C159470946 @default.
- W2045005503 hasConceptScore W2045005503C197534660 @default.