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- W2045012862 abstract "Abstract 1. 1|The function of salivary cooling, vasodilation and behavioural thermoregulation, the preoptic heat sensitivity and the skin heat sensitivity were studied in rats pretreated with 250–310 mg kg −1 capsaicin. All these heat-dissipating mechanisms were impaired, although, the tail vasodilation response to the heat was not totally abolished. 2. 2|Local heating of the preoptic region elicited significantly less vasodilation than in the control animals. 3. 3|Capsaicin micro-injections into the preoptic region induced tail vasodilatation and EEG spindle activity in the intact animals, but not after capsaicin pretreatment. 4. 4|Capsaicin-treated rats showed difficulty in learning a heat-discrimination problem whereas they were as competent as the controls in a learning visual-discrimination task. 5. 5|The results support the suggestion that capsaicin interferes with heat sensors both centrally and peripherally." @default.
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- W2045012862 date "1983-01-01" @default.
- W2045012862 modified "2023-09-27" @default.
- W2045012862 title "Central and peripheral impairment of thermoregulation after capsaicin treatment" @default.
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- W2045012862 doi "https://doi.org/10.1016/0306-4565(83)90105-5" @default.
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