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- W2045052014 abstract "Oxygen tensions were measured in vivo within the different layers of the rainbow trout retina. Oxygen microelectrodes were advanced in 10 μm increments through the retinas and the PO2 measured at each location. Mean retinal PO2 ranged from 124 mm Hg at the retinal-vitreal interface to 281 mm Hg at the choriocapillaris. These data reaffirm that the cellular layers of the normal trout retina are continually exposed to supra-arterial oxygen tensions that are known to cause toxicity in other species. The intraretinal PO2 gradient was mathematically characerized and results indicate that the in vivo oxygen profile can be described by a two-component exponential function. In order to gain a better understanding of oxygen delivery to the retina, the data were also subjected to an analysis based upon the classical equation for planar diffusion. The trout retina is an excellent model for studying oxygen diffusion in vivo since this tissue is supplied with oxygen from a single source, thereby simplifying the mathematical analysis. Calculations yielded values of 1·86 × 10−5 and 0·58 × 10−5 ml O2 min−1 cm−1 atm−1 (at 9°C) for the Krogh permeation coefficient (DS) for the photoreceptor region and the remaining neural retina, respectively." @default.
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- W2045052014 date "1985-11-01" @default.
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- W2045052014 title "Oxygen diffusion in the trout retina" @default.
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- W2045052014 doi "https://doi.org/10.1016/0014-4835(85)90033-8" @default.
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