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- W2045119060 abstract "The study of specialized nutritional support using pharmaconutrients including glutamine, arginine, ω-3 fatty acids, nucleic acids, and growth hormone has grown exponentially over the past several years. Recently, studies have shown that the use of glutamine can decrease bacterial translocation, support glutathione stores, and affect protein synthesis and degradation. Clinically, glutamine supplementation has been shown to reduce hospital stay. Arginine enhances nitrogen balance and has complex effects on the immune system, but evidence of clinical benefit is limited, ω-3 Fatty acids, in the form of fish oil, reduce cholesterol and triglyceride levels and augment the inflammatory response; however, recent work suggests that their clinical effects on coronary artery disease are somewhat equivocal compared with earlier favorable reports. Growth hormone has been shown to enhance nitrogen balance, increase protein synthesis, and stimulate insulin-like growth factor 1 production. Combination regimens using these nutrients have shown promising effects on infectious complications and clinical outcome in specific patient subgroups. Continued research is ongoing to determine the indications and optimal use of these new pharmaconutrients." @default.
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- W2045119060 title "Status and clinical utility of pharmaconutrients" @default.
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