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- W2045123260 abstract "In an exponentially growing culture of E. coli , the concentration of cyclic guanosine 3′:5′-monophosphate (cyclic GMP) was found to increase in parallel with the bacterial growth. As the cells approach the stationary phase of growth, the increment of cyclic GMP also ceases progressively to reach to a plateau. When cells are separated from the medium by centrifugation, almost all of the cyclic GMP is recovered in the culture supernatant. The amount of cyclic GMP accumulated is proportional to the number of cells present in the culture. These results suggest that a constant number of cyclic GMP molecules is synthesized each generation of E. coli , and is excreted from the cells to accumulate into the medium." @default.
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- W2045123260 date "1976-01-01" @default.
- W2045123260 modified "2023-09-27" @default.
- W2045123260 title "Accumulation of cyclic guanosine 3′:5′-monophosphate in the culture medium of growing cells of Escherichia coli" @default.
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- W2045123260 doi "https://doi.org/10.1016/0006-291x(76)91163-3" @default.
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