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- W2045126749 abstract "We studied the brain uptake of a new 2-amino-2-oxazolamines derivative (COR3224) in the rat by means of the rapid intracarotid injection technique described by Oldendorf. The brain uptake index (BUI) of labelled COR3224 decreased progressively from 10% to 5% when concentrations of unlabelled compound were increased. The effect of various compounds indicated that COR3224 is transported into the brain by the purine carrier. The affinity of COR3224 for this carrier (Km = 5.68 μM was higher than that of adenine." @default.
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- W2045126749 date "1991-07-01" @default.
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- W2045126749 title "In vivo evidence for carrier-mediated brain uptake of a new 2-amino-2-oxazoline) via the purine transport system in rat" @default.
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- W2045126749 doi "https://doi.org/10.1016/0006-8993(91)90212-e" @default.
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