FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045132908> ?p ?o ?g. }

• W2045132908 endingPage "71" @default.
• W2045132908 startingPage "33" @default.
• W2045132908 abstract "A quantitative ultrastructural study has been made of the reaction of the incoming synapses of small granule-containing cells after axotomy of the major post-ganglionic branches of the superior cervical ganglion of the young adult rat. These cells are intrinsic and interneurone-like in this ganglion, receiving a preganglionic input and giving outgoing synapses to principal post-ganglionic neurones. Unlike their outgoing synapses, which are lost after post-ganglionic axotomy (Case & Matthews, 1986), the incoming synapses of the small granule-containing cells in axotomized ganglia increased in incidence post-operatively. The increase first became clearly evident 5-7 days post-operatively and was greater, being both more sustained and progressive, after bilateral than after unilateral axotomy. After bilateral axotomy the incidence of incoming synapses rose to more than four times that of normal ganglia and was still elevated at 128 days post-operatively, but was within normal limits at 390 days. After a unilateral lesion, increases of similar extent and time course to those in the axotomized ganglia were seen in the incoming synapses of small granule-containing cells in the uninjured contralateral ganglia. The incoming synapses of the small granule-containing cells are multifocal, i.e. show several points or active foci of synaptic specialization. The increase in synapses expressed itself both through an increased incidence of these synaptic active foci per nerve terminal and through an increase in the number of presynaptic nerve terminal profiles associated with the cells. Control observations indicated that the increase in synapses was not due to surgical stress, nor was it attributable solely to post-operative ageing. The nerve terminals which were presynaptic to the small granule-containing cells post-operatively were all of preganglionic origin: no incoming synapses or presynaptic nerve terminals remained at 2 days after a preganglionic denervation of axotomized or contralateral ganglia, at whatever stage this was performed throughout the range of survival intervals. There was some evidence that the synapses had increased by sprouting, including terminal sprouting, of the preganglionic nerve fibres. In the shorter term there was an increase in the proportion of small nerve terminal profiles. In the longer term the mean size of the terminal profiles increased, and very large terminals of unusual form were seen. After post-ganglionic axotomy, and in particular after a bilateral lesion, the small granule-containing cells became hypertrophied.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
• W2045132908 created "2016-06-24" @default.
• W2045132908 creator A5029317911 @default.
• W2045132908 creator A5034977753 @default.
• W2045132908 date "1986-05-01" @default.
• W2045132908 modified "2023-09-25" @default.
• W2045132908 title "Incoming synapses and size of small granule-containing cells in a rat sympathetic ganglion after post-ganglionic axotomy." @default.
• W2045132908 cites W1499152524 @default.
• W2045132908 cites W1513983649 @default.
• W2045132908 cites W1850059401 @default.
• W2045132908 cites W1895138898 @default.
• W2045132908 cites W1965221759 @default.
• W2045132908 cites W1969958128 @default.
• W2045132908 cites W1973339909 @default.
• W2045132908 cites W1978363078 @default.
• W2045132908 cites W1978484360 @default.
• W2045132908 cites W1980008693 @default.
• W2045132908 cites W1983157149 @default.
• W2045132908 cites W1983441282 @default.
• W2045132908 cites W1983501928 @default.
• W2045132908 cites W1984077238 @default.
• W2045132908 cites W1984113974 @default.
• W2045132908 cites W1987572908 @default.
• W2045132908 cites W1988666686 @default.
• W2045132908 cites W1988842990 @default.
• W2045132908 cites W1994385474 @default.
• W2045132908 cites W1994577340 @default.
• W2045132908 cites W2000492182 @default.
• W2045132908 cites W2007169348 @default.
• W2045132908 cites W2007336130 @default.
• W2045132908 cites W2009274120 @default.
• W2045132908 cites W2010468410 @default.
• W2045132908 cites W2011925126 @default.
• W2045132908 cites W2019734376 @default.
• W2045132908 cites W2021731582 @default.
• W2045132908 cites W2024649683 @default.
• W2045132908 cites W2028491022 @default.
• W2045132908 cites W2030380478 @default.
• W2045132908 cites W2033243555 @default.
• W2045132908 cites W2036491149 @default.
• W2045132908 cites W2038681244 @default.
• W2045132908 cites W2039201169 @default.
• W2045132908 cites W2041402068 @default.
• W2045132908 cites W2043275837 @default.
• W2045132908 cites W2045190423 @default.
• W2045132908 cites W2047893511 @default.
• W2045132908 cites W2053960727 @default.
• W2045132908 cites W2054980542 @default.
• W2045132908 cites W2056654606 @default.
• W2045132908 cites W2057842082 @default.
• W2045132908 cites W2060536413 @default.
• W2045132908 cites W2062576971 @default.
• W2045132908 cites W2063468087 @default.
• W2045132908 cites W2075195343 @default.
• W2045132908 cites W2088494357 @default.
• W2045132908 cites W2121674463 @default.
• W2045132908 cites W2122116963 @default.
• W2045132908 cites W2131209631 @default.
• W2045132908 cites W2134022846 @default.
• W2045132908 cites W2143395795 @default.
• W2045132908 cites W2160326897 @default.
• W2045132908 cites W2402171901 @default.
• W2045132908 cites W2407908302 @default.
• W2045132908 cites W2410323403 @default.
• W2045132908 cites W2414240667 @default.
• W2045132908 cites W2422596987 @default.
• W2045132908 cites W2430410700 @default.
• W2045132908 cites W2436271210 @default.
• W2045132908 cites W7999146 @default.
• W2045132908 doi "https://doi.org/10.1113/jphysiol.1986.sp016065" @default.
• W2045132908 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1182706" @default.
• W2045132908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3746691" @default.
• W2045132908 hasPublicationYear "1986" @default.
• W2045132908 type Work @default.
• W2045132908 sameAs 2045132908 @default.
• W2045132908 citedByCount "9" @default.
• W2045132908 countsByYear W20451329082015 @default.
• W2045132908 crossrefType "journal-article" @default.
• W2045132908 hasAuthorship W2045132908A5029317911 @default.
• W2045132908 hasAuthorship W2045132908A5034977753 @default.
• W2045132908 hasBestOaLocation W20451329081 @default.
• W2045132908 hasConcept C105702510 @default.
• W2045132908 hasConcept C142724271 @default.
• W2045132908 hasConcept C169760540 @default.
• W2045132908 hasConcept C2777646271 @default.
• W2045132908 hasConcept C2778993773 @default.
• W2045132908 hasConcept C2779683492 @default.
• W2045132908 hasConcept C2781156865 @default.
• W2045132908 hasConcept C2781334511 @default.
• W2045132908 hasConcept C529278444 @default.
• W2045132908 hasConcept C71924100 @default.
• W2045132908 hasConcept C86803240 @default.
• W2045132908 hasConceptScore W2045132908C105702510 @default.
• W2045132908 hasConceptScore W2045132908C142724271 @default.
• W2045132908 hasConceptScore W2045132908C169760540 @default.
• W2045132908 hasConceptScore W2045132908C2777646271 @default.
• W2045132908 hasConceptScore W2045132908C2778993773 @default.
• W2045132908 hasConceptScore W2045132908C2779683492 @default.

• next