Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045133093> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2045133093 endingPage "677" @default.
- W2045133093 startingPage "673" @default.
- W2045133093 abstract "Correlation between the gross classification of hepatocellular carcinoma (HCC) and its vascular invasion or intrahepatic metastasis has been reported previously. Because E-cadherin-mediated epithelial cell-to-cell adhesion is thought to suppress cancer cell invasion, the present study was performed to analyze the correlation between E-cadherin expression and the gross classification of HCC.Thirty-six resected solitary HCC <6 cm in diameter were each classified as single nodular type (type 1), single nodular with extranodular growth type (type 2) or contiguous multinodular type (type 3), and the clinicopathological and prognostic differences between type 1 HCC and the other types were analyzed. The expression of E-cadherin in each tumor was examined by immunoblotting and immunohistochemical analysis.Vascular invasion and microscopic intrahepatic metastasis were observed more frequently in types 2 and 3 (61%) than in type 1 (13%) HCC. Immunoblot analysis indicated that the relative level of E-cadherin expression in cancerous tissue was significantly lower in type 2 and 3 (0.75 +/- 0.49) than in type 1 (1.46 +/- 0.79) HCC. Immunohistochemical examination revealed decreased and partially absent E-cadherin expression in the tumorous area of type 2 and 3 HCC. The recurrence-free survival rate was higher for patients with type 1 HCC than for those with the other types.Types 2 and 3 HCC have marked metastatic and invasive potential and reduced expression of E-cadherin, predicting a high risk of recurrence after surgical treatment." @default.
- W2045133093 created "2016-06-24" @default.
- W2045133093 creator A5010825344 @default.
- W2045133093 creator A5069577761 @default.
- W2045133093 creator A5070039951 @default.
- W2045133093 creator A5080725047 @default.
- W2045133093 creator A5081225839 @default.
- W2045133093 creator A5081341214 @default.
- W2045133093 creator A5087376756 @default.
- W2045133093 date "2003-05-09" @default.
- W2045133093 modified "2023-10-16" @default.
- W2045133093 title "Gross appearance of hepatocellular carcinoma reflects E-cadherin expression and risk of early recurrence after surgical treatment" @default.
- W2045133093 cites W1964595762 @default.
- W2045133093 cites W1976820549 @default.
- W2045133093 cites W2012707575 @default.
- W2045133093 cites W2020323099 @default.
- W2045133093 cites W2026262319 @default.
- W2045133093 cites W2061385217 @default.
- W2045133093 cites W2077317303 @default.
- W2045133093 cites W2082623428 @default.
- W2045133093 cites W2086220837 @default.
- W2045133093 cites W2144980110 @default.
- W2045133093 cites W2160356573 @default.
- W2045133093 cites W2312413961 @default.
- W2045133093 doi "https://doi.org/10.1046/j.1440-1746.2003.03021.x" @default.
- W2045133093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12753149" @default.
- W2045133093 hasPublicationYear "2003" @default.
- W2045133093 type Work @default.
- W2045133093 sameAs 2045133093 @default.
- W2045133093 citedByCount "52" @default.
- W2045133093 countsByYear W20451330932012 @default.
- W2045133093 countsByYear W20451330932014 @default.
- W2045133093 countsByYear W20451330932015 @default.
- W2045133093 countsByYear W20451330932016 @default.
- W2045133093 countsByYear W20451330932017 @default.
- W2045133093 countsByYear W20451330932018 @default.
- W2045133093 countsByYear W20451330932019 @default.
- W2045133093 countsByYear W20451330932020 @default.
- W2045133093 countsByYear W20451330932021 @default.
- W2045133093 countsByYear W20451330932023 @default.
- W2045133093 crossrefType "journal-article" @default.
- W2045133093 hasAuthorship W2045133093A5010825344 @default.
- W2045133093 hasAuthorship W2045133093A5069577761 @default.
- W2045133093 hasAuthorship W2045133093A5070039951 @default.
- W2045133093 hasAuthorship W2045133093A5080725047 @default.
- W2045133093 hasAuthorship W2045133093A5081225839 @default.
- W2045133093 hasAuthorship W2045133093A5081341214 @default.
- W2045133093 hasAuthorship W2045133093A5087376756 @default.
- W2045133093 hasConcept C121608353 @default.
- W2045133093 hasConcept C126322002 @default.
- W2045133093 hasConcept C142724271 @default.
- W2045133093 hasConcept C143998085 @default.
- W2045133093 hasConcept C1491633281 @default.
- W2045133093 hasConcept C149402561 @default.
- W2045133093 hasConcept C204232928 @default.
- W2045133093 hasConcept C2777546739 @default.
- W2045133093 hasConcept C2778019345 @default.
- W2045133093 hasConcept C2779013556 @default.
- W2045133093 hasConcept C54355233 @default.
- W2045133093 hasConcept C71924100 @default.
- W2045133093 hasConcept C86803240 @default.
- W2045133093 hasConceptScore W2045133093C121608353 @default.
- W2045133093 hasConceptScore W2045133093C126322002 @default.
- W2045133093 hasConceptScore W2045133093C142724271 @default.
- W2045133093 hasConceptScore W2045133093C143998085 @default.
- W2045133093 hasConceptScore W2045133093C1491633281 @default.
- W2045133093 hasConceptScore W2045133093C149402561 @default.
- W2045133093 hasConceptScore W2045133093C204232928 @default.
- W2045133093 hasConceptScore W2045133093C2777546739 @default.
- W2045133093 hasConceptScore W2045133093C2778019345 @default.
- W2045133093 hasConceptScore W2045133093C2779013556 @default.
- W2045133093 hasConceptScore W2045133093C54355233 @default.
- W2045133093 hasConceptScore W2045133093C71924100 @default.
- W2045133093 hasConceptScore W2045133093C86803240 @default.
- W2045133093 hasIssue "6" @default.
- W2045133093 hasLocation W20451330931 @default.
- W2045133093 hasLocation W20451330932 @default.
- W2045133093 hasOpenAccess W2045133093 @default.
- W2045133093 hasPrimaryLocation W20451330931 @default.
- W2045133093 hasRelatedWork W1570838273 @default.
- W2045133093 hasRelatedWork W1854860614 @default.
- W2045133093 hasRelatedWork W1965733807 @default.
- W2045133093 hasRelatedWork W1991681682 @default.
- W2045133093 hasRelatedWork W2040657853 @default.
- W2045133093 hasRelatedWork W2044517944 @default.
- W2045133093 hasRelatedWork W2349793685 @default.
- W2045133093 hasRelatedWork W2417822880 @default.
- W2045133093 hasRelatedWork W2809701302 @default.
- W2045133093 hasRelatedWork W628600844 @default.
- W2045133093 hasVolume "18" @default.
- W2045133093 isParatext "false" @default.
- W2045133093 isRetracted "false" @default.
- W2045133093 magId "2045133093" @default.
- W2045133093 workType "article" @default.