FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045139780> ?p ?o ?g. }

• W2045139780 endingPage "562" @default.
• W2045139780 startingPage "551" @default.
• W2045139780 abstract "Mosquito larvae exhibit luminal pH extremes along the axial length of their alimentary canal that range from very alkaline (pH>10) in the anterior midgut to slightly acid in the hindgut. The principal buffer in the system is thought to be bicarbonate and/or carbonate, because the lumen is known to contain high levels of bicarbonate/carbonate and is surrounded by various epithelial cell types which express a variety of carbonic anhydrases. However, the precise mechanisms responsible for the transport of bicarbonate/carbonate into and out of the lumen are unclear. In the present study, we test the hypothesis that SLC4-like anion transporters play a role in bicarbonate/carbonate accumulation in the larval mosquito alimentary canal. Molecular, physiological and immnuohistochemical characterizations of Slc4-like transporters in the gut of larval mosquitoes (Aedes aegypti and Anopheles gambiae) demonstrate the presence of both a Na(+)-independent chloride/bicarbonate anion exchanger (AE) as well as a Na(+)-dependent anion exchanger (NDAE). Notably, immunolocalization experiments in Malpighian tubules show that the two proteins can be located in the same tissue, but to different cell types. Immunolabeling experiments in the gastric caecae show that the two proteins can be found in the same cells, but on opposite sides (basal vs. apical). In summary, our results indicate that the alimentary canal of larval mosquitoes exhibits robust expression of two SLC4-like transporters in locations that are consistent with a role in the regulation of luminal pH. The precise physiological contributions of each transporter remain to be determined." @default.
• W2045139780 created "2016-06-24" @default.
• W2045139780 creator A5005522153 @default.
• W2045139780 creator A5010116834 @default.
• W2045139780 creator A5026641159 @default.
• W2045139780 creator A5041914018 @default.
• W2045139780 creator A5049262857 @default.
• W2045139780 creator A5083441262 @default.
• W2045139780 creator A5088811924 @default.
• W2045139780 date "2012-04-01" @default.
• W2045139780 modified "2023-09-27" @default.
• W2045139780 title "Slc4-like anion transporters of the larval mosquito alimentary canal" @default.
• W2045139780 cites W1586193028 @default.
• W2045139780 cites W1693699335 @default.
• W2045139780 cites W1879243208 @default.
• W2045139780 cites W1904902384 @default.
• W2045139780 cites W1907060876 @default.
• W2045139780 cites W1912821000 @default.
• W2045139780 cites W1915376905 @default.
• W2045139780 cites W1972819254 @default.
• W2045139780 cites W1984284836 @default.
• W2045139780 cites W1992790401 @default.
• W2045139780 cites W1992962615 @default.
• W2045139780 cites W1999195948 @default.
• W2045139780 cites W2024229425 @default.
• W2045139780 cites W2025613264 @default.
• W2045139780 cites W2039469985 @default.
• W2045139780 cites W2075428246 @default.
• W2045139780 cites W2083385352 @default.
• W2045139780 cites W2091025692 @default.
• W2045139780 cites W2095758052 @default.
• W2045139780 cites W2101625991 @default.
• W2045139780 cites W2105988299 @default.
• W2045139780 cites W2117936709 @default.
• W2045139780 cites W2119164873 @default.
• W2045139780 cites W2123787197 @default.
• W2045139780 cites W2124342688 @default.
• W2045139780 cites W2134820311 @default.
• W2045139780 cites W2143530569 @default.
• W2045139780 cites W2147879872 @default.
• W2045139780 cites W2154565625 @default.
• W2045139780 cites W2171158206 @default.
• W2045139780 cites W2334433619 @default.
• W2045139780 cites W2419480933 @default.
• W2045139780 cites W2426212166 @default.
• W2045139780 doi "https://doi.org/10.1016/j.jinsphys.2012.01.002" @default.
• W2045139780 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3322255" @default.
• W2045139780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22251674" @default.
• W2045139780 hasPublicationYear "2012" @default.
• W2045139780 type Work @default.
• W2045139780 sameAs 2045139780 @default.
• W2045139780 citedByCount "18" @default.
• W2045139780 countsByYear W20451397802012 @default.
• W2045139780 countsByYear W20451397802013 @default.
• W2045139780 countsByYear W20451397802014 @default.
• W2045139780 countsByYear W20451397802015 @default.
• W2045139780 countsByYear W20451397802016 @default.
• W2045139780 countsByYear W20451397802017 @default.
• W2045139780 countsByYear W20451397802020 @default.
• W2045139780 countsByYear W20451397802021 @default.
• W2045139780 countsByYear W20451397802023 @default.
• W2045139780 crossrefType "journal-article" @default.
• W2045139780 hasAuthorship W2045139780A5005522153 @default.
• W2045139780 hasAuthorship W2045139780A5010116834 @default.
• W2045139780 hasAuthorship W2045139780A5026641159 @default.
• W2045139780 hasAuthorship W2045139780A5041914018 @default.
• W2045139780 hasAuthorship W2045139780A5049262857 @default.
• W2045139780 hasAuthorship W2045139780A5083441262 @default.
• W2045139780 hasAuthorship W2045139780A5088811924 @default.
• W2045139780 hasBestOaLocation W20451397802 @default.
• W2045139780 hasConcept C104317684 @default.
• W2045139780 hasConcept C12554922 @default.
• W2045139780 hasConcept C134018914 @default.
• W2045139780 hasConcept C149011108 @default.
• W2045139780 hasConcept C150149183 @default.
• W2045139780 hasConcept C173758957 @default.
• W2045139780 hasConcept C22145727 @default.
• W2045139780 hasConcept C2777775583 @default.
• W2045139780 hasConcept C2781112554 @default.
• W2045139780 hasConcept C55493867 @default.
• W2045139780 hasConcept C59822182 @default.
• W2045139780 hasConcept C86803240 @default.
• W2045139780 hasConcept C95444343 @default.
• W2045139780 hasConceptScore W2045139780C104317684 @default.
• W2045139780 hasConceptScore W2045139780C12554922 @default.
• W2045139780 hasConceptScore W2045139780C134018914 @default.
• W2045139780 hasConceptScore W2045139780C149011108 @default.
• W2045139780 hasConceptScore W2045139780C150149183 @default.
• W2045139780 hasConceptScore W2045139780C173758957 @default.
• W2045139780 hasConceptScore W2045139780C22145727 @default.
• W2045139780 hasConceptScore W2045139780C2777775583 @default.
• W2045139780 hasConceptScore W2045139780C2781112554 @default.
• W2045139780 hasConceptScore W2045139780C55493867 @default.
• W2045139780 hasConceptScore W2045139780C59822182 @default.
• W2045139780 hasConceptScore W2045139780C86803240 @default.
• W2045139780 hasConceptScore W2045139780C95444343 @default.
• W2045139780 hasIssue "4" @default.
• W2045139780 hasLocation W20451397801 @default.

• next