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- W2045152066 abstract "A series of 4β-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues have been synthesized with high regio-selectivity by employing copper(I)-catalyzed 1,3-dipolar cycloaddition of 1-O-propargyl monosaccharides with C4β-azido podophyllotoxin and C4β-azido-4′-O-demethyl podophyllotoxin. All the compounds were evaluated for their anticancer activity against a panel of six human cancer cell lines. Among these, 4′-O-demethyl podophyllotoxin congeners are showing promising anticancer activity mainly against HCT-15 (colon) and DU-145 (prostate) cells." @default.
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- W2045152066 date "2008-02-01" @default.
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- W2045152066 title "Design, Synthesis, and Biological Testing of 4β-[(4-Substituted)-1,2,3-triazol-1-yl]podophyllotoxin Analogues as Antitumor Agents" @default.
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- W2045152066 doi "https://doi.org/10.1002/ardp.200700116" @default.
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