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• W2045161874 startingPage "682" @default.
• W2045161874 abstract "A parallel 5′-d(TGGGGT)-3′ quadruplex was formed in Na+ solution and crystallized using lithium sulfate as the main precipitating agent. The X-ray structure was determined to 1.5 Å resolution in space group P21 by molecular replacement. The asymmetric unit consists of a characteristic motif of two quadruplexes stacked at their 5′ ends. All nucleotides are clearly defined in the density and could be positioned. A single bound Li+ ion is observed at the surface of the column formed by the two joined molecules. Thus, this small alkali metal ion appears to be unsuitable as a replacement for the Na+ ion in the central channel of G-quartets, unlike K+ or Tl+ ions. A well conserved constellation of water molecules is observed in the grooves of the dimeric structure." @default.
• W2045161874 created "2016-06-24" @default.
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• W2045161874 date "2007-05-15" @default.
• W2045161874 modified "2023-10-13" @default.
• W2045161874 title "Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li⁺ions" @default.
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• W2045161874 doi "https://doi.org/10.1107/s0907444907013315" @default.
• W2045161874 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17505106" @default.
• W2045161874 hasPublicationYear "2007" @default.
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