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• W2045163743 abstract "The neurological syndrome that occurs most commonly in patients with a spinal angioma is gradual in onset, but progresses steadily until there is clinical evidence of an extensive lesion in both longitudinal and transverse axes of the spinal cord. The pathophysiological basis of this is difficult to account for by prevailing theories. We suggest that there is a reduced arteriovenous pressure gradient due to an increase in venous pressure resulting from the anomalous shunt; this, in turn, leads to a reduced intramedullary blood flow, and thus to ischaemic hypoxia. This theory provides an explanation of many of the previously ill-understood clinical and pathological features of these patients. It receives corroborative support from the pathological findings we describe in a case of spinal angioma." @default.
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• W2045163743 date "1974-10-01" @default.
• W2045163743 modified "2023-10-01" @default.
• W2045163743 title "The pathophysiology of spinal vascular malformations" @default.
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• W2045163743 doi "https://doi.org/10.1016/0022-510x(74)90229-9" @default.
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