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- W2045166084 abstract "Auxotyping and serogrouping by coagglutination were used to characterize penicillinase-producing Neisseria gonorrhoeae and penicillinase-negative isolates from the state of Washington, Shreveport (Louisiana), and the Far East. Fifty-four of 75 penicillinase-producing isolates (72 per cent) from Washington required proline for growth and were serogroup W-I (Pro-I), the predominant type of penicillinase-producing strains in the Philippines; none of 86 penicillinase-negative isolates from Washington was Pro-I (P<0.0001). All 38 penicillinase-producing isolates from Shreveport required proline and were serogroup W-II (Pro-II); five of 26 penicillinase-negative isolates (19 per cent) from Shreveport were also Pro-II (P<0.0001) but had antigenic specificities within serogroup W-II that distinguished them from the penicillinase-producing isolates. We conclude that the Washington and Shreveport outbreaks resulted from the spread of imported strains rather than transmission of penicillinase-encoding plasmids to indigenous gonococci. The Shreveport outbreak involved a single strain of penicillinase-producing N. gonorrhoeae and probably originated from a common source, whereas several types were involved in the multiple-source Washington outbreak, indicating repeated introduction of new strains. (N Engl J Med. 1982; 306:950–4.)" @default.
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- W2045166084 date "1982-04-22" @default.
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- W2045166084 title "Epidemiology of Penicillinase-Producing<i>Neisseria gonorrhoeae</i>Infections" @default.
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- W2045166084 doi "https://doi.org/10.1056/nejm198204223061602" @default.
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