Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045173691> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2045173691 endingPage "159" @default.
- W2045173691 startingPage "151" @default.
- W2045173691 abstract "‘Interdigitation’ is a term coined to describe the phenomenon whereby pure phosphatidylcholines with intramolecular fatty acid chain length heterogeneity when hydrated to form bilayers may insert the methyl ends of long fatty acids from one side across more than half of the membrane thickness to protrude amongst the acyl chains of the opposite side of the bilayer (Keough, K.M.W. and Davis, P.J. (1979) Biochemistry 18, 1453–1459; Huang, C. and Mason, J.T. (1986) Biochim. Biophys. Acta 864, 423–470). In this article we address the fate of long fatty acid chains of glycosphingolipids present as minor components in membranes of non-interdigitating phosphatidylcholines. In this pursuit, derivatives of galactosyl ceramide, lactosyl ceramide, globoside and GM1 were synthesized having either 18-carbon or 24-carbon fatty acid with a spin label covalently attached at C-16. Labelled glycolipids were incorporated at 1–2 mol% into bilayers of synthetic phosphatidylcholines, their mixtures with cholesterol, or natural egg phosphatidylcholine. In each case the C-16 carbon of the glycolipid long chain fatty acid showed considerably greater /lsorder/rs and immobility than did C-16 of the fatty acid which was similar in length to the host matrix phospholipids. We interpret this as strong evidence that the long chain fatty acid interdigitates across the mid point of the bilayer in the systems studied. Clearly this phenomenon did not require that the phospholipid host matrix have mixed chain lengths. Furthermore it was totally independent of glycolipid family: for a given host matrix and (glycolipid) fatty acid chain length the order parameter values found were the same amongst all four glycolipid families tested." @default.
- W2045173691 created "2016-06-24" @default.
- W2045173691 creator A5007369439 @default.
- W2045173691 creator A5038627679 @default.
- W2045173691 creator A5041127197 @default.
- W2045173691 creator A5071594661 @default.
- W2045173691 creator A5082589742 @default.
- W2045173691 date "1988-03-01" @default.
- W2045173691 modified "2023-09-27" @default.
- W2045173691 title "Evidence that trans-bilayer interdigitation of glycosphingolipid long chain fatty acids may be a general phenomenon" @default.
- W2045173691 cites W1442294086 @default.
- W2045173691 cites W1967151913 @default.
- W2045173691 cites W1968006848 @default.
- W2045173691 cites W1982071945 @default.
- W2045173691 cites W1984632376 @default.
- W2045173691 cites W1992904138 @default.
- W2045173691 cites W2000113542 @default.
- W2045173691 cites W2024283184 @default.
- W2045173691 cites W2030699384 @default.
- W2045173691 cites W2040658341 @default.
- W2045173691 cites W2043701191 @default.
- W2045173691 cites W2046025180 @default.
- W2045173691 cites W2064048353 @default.
- W2045173691 cites W2067785217 @default.
- W2045173691 cites W2073855039 @default.
- W2045173691 cites W2074859109 @default.
- W2045173691 cites W2083579228 @default.
- W2045173691 cites W2088359206 @default.
- W2045173691 cites W2106370142 @default.
- W2045173691 cites W2218717935 @default.
- W2045173691 cites W2330852220 @default.
- W2045173691 doi "https://doi.org/10.1016/0005-2736(88)90056-9" @default.
- W2045173691 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3349077" @default.
- W2045173691 hasPublicationYear "1988" @default.
- W2045173691 type Work @default.
- W2045173691 sameAs 2045173691 @default.
- W2045173691 citedByCount "58" @default.
- W2045173691 countsByYear W20451736912012 @default.
- W2045173691 countsByYear W20451736912014 @default.
- W2045173691 countsByYear W20451736912015 @default.
- W2045173691 countsByYear W20451736912017 @default.
- W2045173691 countsByYear W20451736912019 @default.
- W2045173691 countsByYear W20451736912020 @default.
- W2045173691 countsByYear W20451736912021 @default.
- W2045173691 crossrefType "journal-article" @default.
- W2045173691 hasAuthorship W2045173691A5007369439 @default.
- W2045173691 hasAuthorship W2045173691A5038627679 @default.
- W2045173691 hasAuthorship W2045173691A5041127197 @default.
- W2045173691 hasAuthorship W2045173691A5071594661 @default.
- W2045173691 hasAuthorship W2045173691A5082589742 @default.
- W2045173691 hasConcept C185592680 @default.
- W2045173691 hasConcept C190283241 @default.
- W2045173691 hasConcept C192157962 @default.
- W2045173691 hasConcept C22222904 @default.
- W2045173691 hasConcept C2776330855 @default.
- W2045173691 hasConcept C2776931407 @default.
- W2045173691 hasConcept C2777851122 @default.
- W2045173691 hasConcept C2778918659 @default.
- W2045173691 hasConcept C39944091 @default.
- W2045173691 hasConcept C41625074 @default.
- W2045173691 hasConcept C543025807 @default.
- W2045173691 hasConcept C55493867 @default.
- W2045173691 hasConcept C71240020 @default.
- W2045173691 hasConceptScore W2045173691C185592680 @default.
- W2045173691 hasConceptScore W2045173691C190283241 @default.
- W2045173691 hasConceptScore W2045173691C192157962 @default.
- W2045173691 hasConceptScore W2045173691C22222904 @default.
- W2045173691 hasConceptScore W2045173691C2776330855 @default.
- W2045173691 hasConceptScore W2045173691C2776931407 @default.
- W2045173691 hasConceptScore W2045173691C2777851122 @default.
- W2045173691 hasConceptScore W2045173691C2778918659 @default.
- W2045173691 hasConceptScore W2045173691C39944091 @default.
- W2045173691 hasConceptScore W2045173691C41625074 @default.
- W2045173691 hasConceptScore W2045173691C543025807 @default.
- W2045173691 hasConceptScore W2045173691C55493867 @default.
- W2045173691 hasConceptScore W2045173691C71240020 @default.
- W2045173691 hasIssue "1" @default.
- W2045173691 hasLocation W20451736911 @default.
- W2045173691 hasLocation W20451736912 @default.
- W2045173691 hasOpenAccess W2045173691 @default.
- W2045173691 hasPrimaryLocation W20451736911 @default.
- W2045173691 hasRelatedWork W1972562981 @default.
- W2045173691 hasRelatedWork W1984871187 @default.
- W2045173691 hasRelatedWork W1989589392 @default.
- W2045173691 hasRelatedWork W1996269868 @default.
- W2045173691 hasRelatedWork W2009240753 @default.
- W2045173691 hasRelatedWork W2012509070 @default.
- W2045173691 hasRelatedWork W2045173691 @default.
- W2045173691 hasRelatedWork W2080172359 @default.
- W2045173691 hasRelatedWork W2461364449 @default.
- W2045173691 hasRelatedWork W2189501190 @default.
- W2045173691 hasVolume "939" @default.
- W2045173691 isParatext "false" @default.
- W2045173691 isRetracted "false" @default.
- W2045173691 magId "2045173691" @default.
- W2045173691 workType "article" @default.