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- W2045240624 abstract "The gastric acid secretion was assessed in 102 consecutive vitiligo patients by means of the augmented histamine test. Achlorhydria was found in 20 patients. 8 of these 20 patients had pernicious anæmia, only 3 of the cases being known before the study. 19 of the 20 patients with achlorhydria and all 8 with pernicious anæmia were women. The frequency of achlorhydria in men with vitiligo was normal. Serum-vitamin-B12 was abnormally low in the patients with pernicious anæmia, low to normal in those with achlorhydria without pernicious anæmia, and normal in acid secretors. Antibody to gastric parietal cells was found in 80% of vitiligo patients with achlorhydria, compared to 6% of a normal group. Antibody to intrinsic factor was found in 3 patients, all of whom had pernicious anæmia. Insulin-dependent diabetes mellitus was found in 4 of the 102 vitiligo patients, and 6 had thyroid disease (including 2 women with Hashimoto's struma)." @default.
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- W2045240624 date "1971-06-01" @default.
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- W2045240624 title "VITILIGO, ACHLORHYDRIA, AND PERNICIOUS ANÆMIA" @default.
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- W2045240624 doi "https://doi.org/10.1016/s0140-6736(71)91889-7" @default.
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