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- W2045261025 abstract "Chick embryos ranging in age from 4.0 to 18 days of incubation and 1–2-day-old hatchlings received injections of HRP solutions directly into the leg musculature. After survival periods of from 5 to 25 h motoneurons and cells in the spinal sensory ganglia were found to be stained with the HRP reaction product. It was found that the first appearance of a positive HRP reaction coincided with the time when nerve processes are first detected in the limb-bud by silver techniques (i.e. at 4.5 days of incubation). Only neurons with processes in the region of injection showed a positive reaction. The demonstration of a retrograde transport mechanism in neurons and axons which are still undergoing growth and differentiation provides a possible mechanism for the peripheral regulation of certain features of CNS neurogenesis. The application of this technique during development may also allow one to map neuroanatomical pathways during their formation." @default.
- W2045261025 created "2016-06-24" @default.
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- W2045261025 date "1975-11-01" @default.
- W2045261025 modified "2023-09-26" @default.
- W2045261025 title "The retrograde transport of horseradish peroxidase from the developing limb of the chick embryo" @default.
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- W2045261025 doi "https://doi.org/10.1016/0006-8993(75)90007-4" @default.
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