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• W2045270037 abstract "One of the key parameters and most difficult challenges related to Microbeam Radiation Therapy (MRT) is the exact measurement of radiation dose delivered. The approach presented here is based on the conversion of the oxidation state of samarium ions (embedded in a suitable glass host) upon exposure to high energy radiation. The conversion from Sm3 + to Sm2 + under the effect of high x-ray irradiation doses has been studied in four oxyfluoride glasses based on Ca, Mg, Sr and Ba. These glasses can easily be prepared in air, contrary to pure fluoride glasses. They provide good transparency in the visible range, essential for analysis by confocal microscopy. Only the Mg-based glasses exhibited a clear conversion of Sm3 + to Sm2 + under x-ray exposure; and hence show potential for use as MRT dosimetry. The conversion did not saturate even up to ~ 20 kGy (dose in air at the sample surface) under a 50 keV synchrotron beam. Further, we were able to determine the spatial dose profile of the x-ray beam through confocal fluoroscopic microscopy; and the dose profile matched closely that from the Monte Carlo simulation." @default.
• W2045270037 created "2016-06-24" @default.
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• W2045270037 date "2013-10-01" @default.
• W2045270037 modified "2023-10-03" @default.
• W2045270037 title "Samarium-doped oxyfluoride borophosphate glasses for x-ray dosimetry in Microbeam Radiation Therapy" @default.
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• W2045270037 doi "https://doi.org/10.1016/j.jnoncrysol.2012.12.015" @default.
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