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- W2045271839 abstract "We read the article by Pang et al<sup>1</sup>concerning the use of frog skin for the differentiation of bullous pemphigoid (BP) from epidermolysis bullosa acquisita (EBA). Based on sporadic observations of a floor-pattern indirect immunofluorescence on 1 mol/L of sodium chloride—split skin (SSS) obtained from BP sera, these authors used skin from a toad to establish a differential diagnosis between BP and EBA. Their rationale was the fact that, as suggested by earlier studies, the BP antigen is present in the skin of some animals,<sup>2</sup>from which the EBA antigen—being phylogenetically more restricted—is absent.<sup>3</sup>Since this procedure seems attractive, we undertook a retrospective comparative study to better delineate the usefulness of animal skin substrates for the diagnosis, using indirect immunofluorescence, of subepidermal autoimmune bullous diseases. During the last 3 years, we screened over 1500 human serum samples sent to us under the suspicion of a subepidermal autoimmune" @default.
- W2045271839 created "2016-06-24" @default.
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- W2045271839 date "1994-12-01" @default.
- W2045271839 modified "2023-09-25" @default.
- W2045271839 title "Use of Animal Skin Substrates for Indirect Immunofluorescence Diagnosis of Subepidermal Autoimmune Bullous Diseases" @default.
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- W2045271839 doi "https://doi.org/10.1001/archderm.1994.01690120102017" @default.
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