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• W2045281567 abstract "Isolated ciliary axonemes from pig trachea were exposed to increasing concentrations of purified Pseudomonas aeruginosa rhamnolipid. This is a defined ciliary system allowing observation of direct impairment of functional axonemes. Axonemal motility and ATPase activity were decreased in proportion to rhamnolipid concentrations. ATPase-associated proteins observed in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and dynein arms seen in ultra-structural cross sections progressively disappeared from axonemes with exposure to rhamnolipid. These four independent measures establish that the rhamnolipid removes the ATPase-containing outer dynein arms from the ciliary axoneme, thereby rendering the axoneme immotile." @default.
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• W2045281567 date "1986-01-01" @default.
• W2045281567 modified "2023-10-18" @default.
• W2045281567 title "Rhamnolipid fromPseudomonas aeruginosa inactivates mammalian tracheal ciliary axonemes" @default.
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• W2045281567 doi "https://doi.org/10.1002/cm.970060509" @default.
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