FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045307661> ?p ?o ?g. }

• W2045307661 endingPage "1153" @default.
• W2045307661 startingPage "1147" @default.
• W2045307661 abstract "BackgroundImmunohistochemical profiles of esophageal and cardia adenocarcinoma differ according to the presence or absence of Barrett's epithelium (BIM) and gastric intestinal metaplasia (GIM) in the fundus and antrum. Different lymphatic spreading has been demonstrated in esophageal adenocarcinoma. We investigated the correlation among the presence or absence of intestinal metaplasia in the esophagus and stomach and lymphatic metastases in patients who underwent radical surgery for esophageal and cardia adenocarcinoma.MethodsThe mucosa surrounding the adenocarcinoma and the gastric mucosa were analyzed. The BIM+ patients underwent subtotal esophagectomy and gastric pull up, and the BIM– patients underwent esophagectomy at the azygos vein, total gastrectomy, and esophagojejunostomy. The radical thoracic (station numbers 2, 3, 4R, 7, 8, and 9) and abdominal (station numbers 15 through 20) lymphadenectomy was identical in both procedures except for the greater curvature.ResultsOne hundred ninety-four consecutive patients were collected in three major groups: BIM+/GIM–, 52 patients (26.8%); BIM–/GIM–, 90 patients (46.4%); BIM–/GIM+, 50 patients (25.8%). Two patients (1%) were BIM+/GIM+. A total of 6,010 lymph nodes were resected: 1,515 were recovered in BIM+, 1,587 in BIM–/GIM+, and 2,908 in BIM–/GIM– patients. The percentage of patients with pN+ stations 8 and 9 was higher in BIM+ (p = 0.001), and the percentage of patients with pN+ perigastric stations was higher in BIM– (p = 0.001). The BIM–/GIM– patients had a number of abdominal metastatic lymph nodes higher than did the BIM–/GIM+ patients (p = 0.0001).ConclusionsAccording to the presence or absence of BIM and GIM in the esophagus and cardia, adenocarcinoma correspond to three different patterns of lymphatic metastasization, which may reflect different biologic and carcinogenetic pathways. Immunohistochemical profiles of esophageal and cardia adenocarcinoma differ according to the presence or absence of Barrett's epithelium (BIM) and gastric intestinal metaplasia (GIM) in the fundus and antrum. Different lymphatic spreading has been demonstrated in esophageal adenocarcinoma. We investigated the correlation among the presence or absence of intestinal metaplasia in the esophagus and stomach and lymphatic metastases in patients who underwent radical surgery for esophageal and cardia adenocarcinoma. The mucosa surrounding the adenocarcinoma and the gastric mucosa were analyzed. The BIM+ patients underwent subtotal esophagectomy and gastric pull up, and the BIM– patients underwent esophagectomy at the azygos vein, total gastrectomy, and esophagojejunostomy. The radical thoracic (station numbers 2, 3, 4R, 7, 8, and 9) and abdominal (station numbers 15 through 20) lymphadenectomy was identical in both procedures except for the greater curvature. One hundred ninety-four consecutive patients were collected in three major groups: BIM+/GIM–, 52 patients (26.8%); BIM–/GIM–, 90 patients (46.4%); BIM–/GIM+, 50 patients (25.8%). Two patients (1%) were BIM+/GIM+. A total of 6,010 lymph nodes were resected: 1,515 were recovered in BIM+, 1,587 in BIM–/GIM+, and 2,908 in BIM–/GIM– patients. The percentage of patients with pN+ stations 8 and 9 was higher in BIM+ (p = 0.001), and the percentage of patients with pN+ perigastric stations was higher in BIM– (p = 0.001). The BIM–/GIM– patients had a number of abdominal metastatic lymph nodes higher than did the BIM–/GIM+ patients (p = 0.0001). According to the presence or absence of BIM and GIM in the esophagus and cardia, adenocarcinoma correspond to three different patterns of lymphatic metastasization, which may reflect different biologic and carcinogenetic pathways." @default.
• W2045307661 created "2016-06-24" @default.
• W2045307661 creator A5009081298 @default.
• W2045307661 creator A5009118816 @default.
• W2045307661 creator A5018206282 @default.
• W2045307661 creator A5041424817 @default.
• W2045307661 creator A5056293658 @default.
• W2045307661 creator A5066058450 @default.
• W2045307661 creator A5075555807 @default.
• W2045307661 creator A5079509071 @default.
• W2045307661 creator A5082685964 @default.
• W2045307661 creator A5086034237 @default.
• W2045307661 date "2013-04-01" @default.
• W2045307661 modified "2023-10-14" @default.
• W2045307661 title "Esophagogastric Metaplasia Relates to Nodal Metastases in Adenocarcinoma of Esophagus and Cardia" @default.
• W2045307661 cites W1977859628 @default.
• W2045307661 cites W1978569786 @default.
• W2045307661 cites W1982323895 @default.
• W2045307661 cites W2000581479 @default.
• W2045307661 cites W2004995987 @default.
• W2045307661 cites W2014705863 @default.
• W2045307661 cites W2016821473 @default.
• W2045307661 cites W2022839455 @default.
• W2045307661 cites W2025848903 @default.
• W2045307661 cites W2034824120 @default.
• W2045307661 cites W2041688782 @default.
• W2045307661 cites W2054059601 @default.
• W2045307661 cites W2055209905 @default.
• W2045307661 cites W2057643894 @default.
• W2045307661 cites W2074023224 @default.
• W2045307661 cites W2078399076 @default.
• W2045307661 cites W2089574951 @default.
• W2045307661 cites W2105689747 @default.
• W2045307661 cites W2130591858 @default.
• W2045307661 cites W2135160082 @default.
• W2045307661 cites W2167028539 @default.
• W2045307661 cites W2948387191 @default.
• W2045307661 doi "https://doi.org/10.1016/j.athoracsur.2012.12.040" @default.
• W2045307661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23434259" @default.
• W2045307661 hasPublicationYear "2013" @default.
• W2045307661 type Work @default.
• W2045307661 sameAs 2045307661 @default.
• W2045307661 citedByCount "9" @default.
• W2045307661 countsByYear W20453076612014 @default.
• W2045307661 countsByYear W20453076612016 @default.
• W2045307661 countsByYear W20453076612017 @default.
• W2045307661 countsByYear W20453076612018 @default.
• W2045307661 countsByYear W20453076612019 @default.
• W2045307661 countsByYear W20453076612020 @default.
• W2045307661 countsByYear W20453076612021 @default.
• W2045307661 crossrefType "journal-article" @default.
• W2045307661 hasAuthorship W2045307661A5009081298 @default.
• W2045307661 hasAuthorship W2045307661A5009118816 @default.
• W2045307661 hasAuthorship W2045307661A5018206282 @default.
• W2045307661 hasAuthorship W2045307661A5041424817 @default.
• W2045307661 hasAuthorship W2045307661A5056293658 @default.
• W2045307661 hasAuthorship W2045307661A5066058450 @default.
• W2045307661 hasAuthorship W2045307661A5075555807 @default.
• W2045307661 hasAuthorship W2045307661A5079509071 @default.
• W2045307661 hasAuthorship W2045307661A5082685964 @default.
• W2045307661 hasAuthorship W2045307661A5086034237 @default.
• W2045307661 hasBestOaLocation W20453076611 @default.
• W2045307661 hasConcept C121608353 @default.
• W2045307661 hasConcept C126322002 @default.
• W2045307661 hasConcept C142724271 @default.
• W2045307661 hasConcept C2776497702 @default.
• W2045307661 hasConcept C2777297899 @default.
• W2045307661 hasConcept C2777819096 @default.
• W2045307661 hasConcept C2778589982 @default.
• W2045307661 hasConcept C2779357193 @default.
• W2045307661 hasConcept C2779422922 @default.
• W2045307661 hasConcept C2779720271 @default.
• W2045307661 hasConcept C2779742542 @default.
• W2045307661 hasConcept C2780470880 @default.
• W2045307661 hasConcept C2781182431 @default.
• W2045307661 hasConcept C35150756 @default.
• W2045307661 hasConcept C71924100 @default.
• W2045307661 hasConcept C90924648 @default.
• W2045307661 hasConceptScore W2045307661C121608353 @default.
• W2045307661 hasConceptScore W2045307661C126322002 @default.
• W2045307661 hasConceptScore W2045307661C142724271 @default.
• W2045307661 hasConceptScore W2045307661C2776497702 @default.
• W2045307661 hasConceptScore W2045307661C2777297899 @default.
• W2045307661 hasConceptScore W2045307661C2777819096 @default.
• W2045307661 hasConceptScore W2045307661C2778589982 @default.
• W2045307661 hasConceptScore W2045307661C2779357193 @default.
• W2045307661 hasConceptScore W2045307661C2779422922 @default.
• W2045307661 hasConceptScore W2045307661C2779720271 @default.
• W2045307661 hasConceptScore W2045307661C2779742542 @default.
• W2045307661 hasConceptScore W2045307661C2780470880 @default.
• W2045307661 hasConceptScore W2045307661C2781182431 @default.
• W2045307661 hasConceptScore W2045307661C35150756 @default.
• W2045307661 hasConceptScore W2045307661C71924100 @default.
• W2045307661 hasConceptScore W2045307661C90924648 @default.
• W2045307661 hasIssue "4" @default.
• W2045307661 hasLocation W20453076611 @default.
• W2045307661 hasLocation W20453076612 @default.
• W2045307661 hasOpenAccess W2045307661 @default.

• next