Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045308183> ?p ?o ?g. }
- W2045308183 endingPage "e1002809" @default.
- W2045308183 startingPage "e1002809" @default.
- W2045308183 abstract "Understanding the principles governing the dynamic coordination of functional brain networks remains an important unmet goal within neuroscience. How do distributed ensembles of neurons transiently coordinate their activity across a variety of spatial and temporal scales? While a complete mechanistic account of this process remains elusive, evidence suggests that neuronal oscillations may play a key role in this process, with different rhythms influencing both local computation and long-range communication. To investigate this question, we recorded multiple single unit and local field potential (LFP) activity from microelectrode arrays implanted bilaterally in macaque motor areas. Monkeys performed a delayed center-out reach task either manually using their natural arm (Manual Control, MC) or under direct neural control through a brain-machine interface (Brain Control, BC). In accord with prior work, we found that the spiking activity of individual neurons is coupled to multiple aspects of the ongoing motor beta rhythm (10-45 Hz) during both MC and BC, with neurons exhibiting a diversity of coupling preferences. However, here we show that for identified single neurons, this beta-to-rate mapping can change in a reversible and task-dependent way. For example, as beta power increases, a given neuron may increase spiking during MC but decrease spiking during BC, or exhibit a reversible shift in the preferred phase of firing. The within-task stability of coupling, combined with the reversible cross-task changes in coupling, suggest that task-dependent changes in the beta-to-rate mapping play a role in the transient functional reorganization of neural ensembles. We characterize the range of task-dependent changes in the mapping from beta amplitude, phase, and inter-hemispheric phase differences to the spike rates of an ensemble of simultaneously-recorded neurons, and discuss the potential implications that dynamic remapping from oscillatory activity to spike rate and timing may hold for models of computation and communication in distributed functional brain networks." @default.
- W2045308183 created "2016-06-24" @default.
- W2045308183 creator A5023230862 @default.
- W2045308183 creator A5024864142 @default.
- W2045308183 creator A5078387994 @default.
- W2045308183 date "2012-12-20" @default.
- W2045308183 modified "2023-10-07" @default.
- W2045308183 title "Task-Dependent Changes in Cross-Level Coupling between Single Neurons and Oscillatory Activity in Multiscale Networks" @default.
- W2045308183 cites W1539683305 @default.
- W2045308183 cites W1559015476 @default.
- W2045308183 cites W1766529490 @default.
- W2045308183 cites W1924056530 @default.
- W2045308183 cites W1963595563 @default.
- W2045308183 cites W1970445701 @default.
- W2045308183 cites W1971101394 @default.
- W2045308183 cites W1971815199 @default.
- W2045308183 cites W1973752972 @default.
- W2045308183 cites W1975947675 @default.
- W2045308183 cites W1976433270 @default.
- W2045308183 cites W1976997622 @default.
- W2045308183 cites W1977628053 @default.
- W2045308183 cites W1978389345 @default.
- W2045308183 cites W1980921958 @default.
- W2045308183 cites W1990973912 @default.
- W2045308183 cites W1994218329 @default.
- W2045308183 cites W1995898274 @default.
- W2045308183 cites W1996874802 @default.
- W2045308183 cites W1998162737 @default.
- W2045308183 cites W2006874412 @default.
- W2045308183 cites W2012661701 @default.
- W2045308183 cites W2016489412 @default.
- W2045308183 cites W2018175367 @default.
- W2045308183 cites W2022704107 @default.
- W2045308183 cites W2025180344 @default.
- W2045308183 cites W2027547971 @default.
- W2045308183 cites W2030345583 @default.
- W2045308183 cites W2032045351 @default.
- W2045308183 cites W2033707011 @default.
- W2045308183 cites W2040739363 @default.
- W2045308183 cites W2043952803 @default.
- W2045308183 cites W2046198005 @default.
- W2045308183 cites W2048272660 @default.
- W2045308183 cites W2050113708 @default.
- W2045308183 cites W2064237091 @default.
- W2045308183 cites W2064869244 @default.
- W2045308183 cites W2069764737 @default.
- W2045308183 cites W2070027623 @default.
- W2045308183 cites W2073200841 @default.
- W2045308183 cites W2083295972 @default.
- W2045308183 cites W2083547018 @default.
- W2045308183 cites W2087822149 @default.
- W2045308183 cites W2088092325 @default.
- W2045308183 cites W2092034545 @default.
- W2045308183 cites W2094850439 @default.
- W2045308183 cites W2099938345 @default.
- W2045308183 cites W2103212315 @default.
- W2045308183 cites W2104731571 @default.
- W2045308183 cites W2107515388 @default.
- W2045308183 cites W2112463907 @default.
- W2045308183 cites W2112601177 @default.
- W2045308183 cites W2115383940 @default.
- W2045308183 cites W2120182026 @default.
- W2045308183 cites W2125737923 @default.
- W2045308183 cites W2126020484 @default.
- W2045308183 cites W2129217278 @default.
- W2045308183 cites W2131367668 @default.
- W2045308183 cites W2133280087 @default.
- W2045308183 cites W2133947591 @default.
- W2045308183 cites W2135681455 @default.
- W2045308183 cites W2135755416 @default.
- W2045308183 cites W2136363447 @default.
- W2045308183 cites W2146693559 @default.
- W2045308183 cites W2151229057 @default.
- W2045308183 cites W2151718948 @default.
- W2045308183 cites W2154697573 @default.
- W2045308183 cites W2157376352 @default.
- W2045308183 cites W2157787057 @default.
- W2045308183 cites W2159799383 @default.
- W2045308183 cites W2159929956 @default.
- W2045308183 cites W2160904011 @default.
- W2045308183 cites W2170814877 @default.
- W2045308183 cites W2171367914 @default.
- W2045308183 cites W2258755109 @default.
- W2045308183 cites W4211251910 @default.
- W2045308183 cites W4298013822 @default.
- W2045308183 doi "https://doi.org/10.1371/journal.pcbi.1002809" @default.
- W2045308183 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3527280" @default.
- W2045308183 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23284276" @default.
- W2045308183 hasPublicationYear "2012" @default.
- W2045308183 type Work @default.
- W2045308183 sameAs 2045308183 @default.
- W2045308183 citedByCount "52" @default.
- W2045308183 countsByYear W20453081832013 @default.
- W2045308183 countsByYear W20453081832014 @default.
- W2045308183 countsByYear W20453081832015 @default.
- W2045308183 countsByYear W20453081832016 @default.
- W2045308183 countsByYear W20453081832017 @default.
- W2045308183 countsByYear W20453081832018 @default.