FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W204530926> ?p ?o ?g. }

• W204530926 abstract "Objective and design Chemotaxis of neutrophils from blood to the inflammation process plays an important role in development of periodontal inflammation. The novel chemokine GROa, also named CXCL1, is a strong chemoattractant for neutrophils. Data on production and regulation of GROa by oral fibroblasts have not previously been presented. Materials and methods GROa mRNA and protein levels were determined in human periodontal ligament cells and mouse gingival fibroblasts by quantitative real-time PCR and ELISA. Results We disclose that both human periodontal ligament cells and mouse gingival fibroblasts produce GROa in response to LPS stimulation. Stimulation with LPS for 24 h increased both mRNA for GROa and GROa protein. The steroid hormone estrogen had no effect on LPS-induced GROa mRNA expression. Treatment with the glucocorticoid dexamethasone attenuated LPS-induced GROa production, and the NF-jB blocker MG 132 fully prevented LPS-induced GROa. Conclusions Oral fibroblasts respond to LPS stimulation by increasing GROa production via the transcription factor NF-jB, suggesting that this mechanism may be involved in development of periodontal inflammation." @default.
• W204530926 created "2016-06-24" @default.
• W204530926 creator A5026514149 @default.
• W204530926 creator A5046132887 @default.
• W204530926 creator A5080739408 @default.
• W204530926 creator A5091208313 @default.
• W204530926 date "2009-01-01" @default.
• W204530926 modified "2023-09-27" @default.
• W204530926 title "LPS induces GROa chemokine production via NF-jB in oral fibroblasts" @default.
• W204530926 cites W1565248052 @default.
• W204530926 cites W1775749144 @default.
• W204530926 cites W1963308541 @default.
• W204530926 cites W1971162837 @default.
• W204530926 cites W1972574171 @default.
• W204530926 cites W1973195685 @default.
• W204530926 cites W1979109301 @default.
• W204530926 cites W1983203261 @default.
• W204530926 cites W1992282800 @default.
• W204530926 cites W1993083632 @default.
• W204530926 cites W2008680963 @default.
• W204530926 cites W2012253186 @default.
• W204530926 cites W2015153980 @default.
• W204530926 cites W2015534647 @default.
• W204530926 cites W2035782815 @default.
• W204530926 cites W2046218793 @default.
• W204530926 cites W2052323412 @default.
• W204530926 cites W2056302913 @default.
• W204530926 cites W2058757949 @default.
• W204530926 cites W2061082603 @default.
• W204530926 cites W2069420314 @default.
• W204530926 cites W2070901955 @default.
• W204530926 cites W2104386484 @default.
• W204530926 cites W2106471110 @default.
• W204530926 cites W2108244474 @default.
• W204530926 cites W2147389799 @default.
• W204530926 cites W2151597066 @default.
• W204530926 cites W2167782689 @default.
• W204530926 cites W2216094174 @default.
• W204530926 hasPublicationYear "2009" @default.
• W204530926 type Work @default.
• W204530926 sameAs 204530926 @default.
• W204530926 citedByCount "0" @default.
• W204530926 crossrefType "journal-article" @default.
• W204530926 hasAuthorship W204530926A5026514149 @default.
• W204530926 hasAuthorship W204530926A5046132887 @default.
• W204530926 hasAuthorship W204530926A5080739408 @default.
• W204530926 hasAuthorship W204530926A5091208313 @default.
• W204530926 hasConcept C126322002 @default.
• W204530926 hasConcept C13373296 @default.
• W204530926 hasConcept C134018914 @default.
• W204530926 hasConcept C170493617 @default.
• W204530926 hasConcept C185592680 @default.
• W204530926 hasConcept C199343813 @default.
• W204530926 hasConcept C202751555 @default.
• W204530926 hasConcept C203014093 @default.
• W204530926 hasConcept C24998067 @default.
• W204530926 hasConcept C2776914184 @default.
• W204530926 hasConcept C2780381497 @default.
• W204530926 hasConcept C2780841215 @default.
• W204530926 hasConcept C41868710 @default.
• W204530926 hasConcept C54166955 @default.
• W204530926 hasConcept C55493867 @default.
• W204530926 hasConcept C68324877 @default.
• W204530926 hasConcept C71924100 @default.
• W204530926 hasConcept C86803240 @default.
• W204530926 hasConcept C95444343 @default.
• W204530926 hasConcept C96525457 @default.
• W204530926 hasConceptScore W204530926C126322002 @default.
• W204530926 hasConceptScore W204530926C13373296 @default.
• W204530926 hasConceptScore W204530926C134018914 @default.
• W204530926 hasConceptScore W204530926C170493617 @default.
• W204530926 hasConceptScore W204530926C185592680 @default.
• W204530926 hasConceptScore W204530926C199343813 @default.
• W204530926 hasConceptScore W204530926C202751555 @default.
• W204530926 hasConceptScore W204530926C203014093 @default.
• W204530926 hasConceptScore W204530926C24998067 @default.
• W204530926 hasConceptScore W204530926C2776914184 @default.
• W204530926 hasConceptScore W204530926C2780381497 @default.
• W204530926 hasConceptScore W204530926C2780841215 @default.
• W204530926 hasConceptScore W204530926C41868710 @default.
• W204530926 hasConceptScore W204530926C54166955 @default.
• W204530926 hasConceptScore W204530926C55493867 @default.
• W204530926 hasConceptScore W204530926C68324877 @default.
• W204530926 hasConceptScore W204530926C71924100 @default.
• W204530926 hasConceptScore W204530926C86803240 @default.
• W204530926 hasConceptScore W204530926C95444343 @default.
• W204530926 hasConceptScore W204530926C96525457 @default.
• W204530926 hasLocation W2045309261 @default.
• W204530926 hasOpenAccess W204530926 @default.
• W204530926 hasPrimaryLocation W2045309261 @default.
• W204530926 hasRelatedWork W1533241047 @default.
• W204530926 hasRelatedWork W1973251022 @default.
• W204530926 hasRelatedWork W1974580491 @default.
• W204530926 hasRelatedWork W2007072161 @default.
• W204530926 hasRelatedWork W2029090980 @default.
• W204530926 hasRelatedWork W2035782815 @default.
• W204530926 hasRelatedWork W2102505909 @default.
• W204530926 hasRelatedWork W2114290117 @default.
• W204530926 hasRelatedWork W2152653506 @default.
• W204530926 hasRelatedWork W2369839965 @default.

• next