FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045337788> ?p ?o ?g. }

• W2045337788 endingPage "4022" @default.
• W2045337788 startingPage "4016" @default.
• W2045337788 abstract "Eclipta prostrata L., (Asteraceae), is used in China for both food and medicine purposes. This research is concerned with the isolation and purification of phytochemical constituents from the aerial parts of E. prostrata, using gradient solvent fractionation, macroporous resin, silica gel, Sephadex LH-20 and ODS columns, and TLC analyses. Four fractions (water, 30% ethanol, 60% ethanol and 90% ethanol) were obtained. Four compounds, wedelolactone (I), eclalbasaponin I (II), luteolin (III) and luteolin-7-O-glucoside (IV) were purified and their structures were identified by the interpretation of spectroscopic analyses including MS, (1)H and (13)C NMR. Antitumor activities of extracts (total fraction), four fractions and the isolated compounds were assessed using hepatoma cell smmc-7721 as an in vitro assay system. The 30% ethanol fraction and eclalbasaponin I dose-dependently inhibited the proliferation of hepatoma cell smmc-7721 with IC(50) values of 74.2399 and 111.1703 μg/ml, respectively, more strongly compared with 5-fluorouracil positive control group with the IC(50) value of 195.3131 μg/ml. Antitumor activities of other fractions and compounds were lower than positive control. These results suggested that some specific compounds or extracts from E. prostrata are potential sources of natural anti-tumor materials and worthy of further study." @default.
• W2045337788 created "2016-06-24" @default.
• W2045337788 creator A5000562106 @default.
• W2045337788 creator A5001190035 @default.
• W2045337788 creator A5054123016 @default.
• W2045337788 creator A5063512998 @default.
• W2045337788 date "2012-11-01" @default.
• W2045337788 modified "2023-10-16" @default.
• W2045337788 title "Eclipta prostrata L. phytochemicals: Isolation, structure elucidation, and their antitumor activity" @default.
• W2045337788 cites W1596699206 @default.
• W2045337788 cites W178016941 @default.
• W2045337788 cites W1979461875 @default.
• W2045337788 cites W1982637906 @default.
• W2045337788 cites W2001254183 @default.
• W2045337788 cites W2001643884 @default.
• W2045337788 cites W2004685279 @default.
• W2045337788 cites W2004898945 @default.
• W2045337788 cites W2007662671 @default.
• W2045337788 cites W2015146412 @default.
• W2045337788 cites W2040684447 @default.
• W2045337788 cites W2049086737 @default.
• W2045337788 cites W2050767955 @default.
• W2045337788 cites W2055009959 @default.
• W2045337788 cites W2055568666 @default.
• W2045337788 cites W2058162754 @default.
• W2045337788 cites W2068334174 @default.
• W2045337788 cites W2086390146 @default.
• W2045337788 cites W2109069677 @default.
• W2045337788 cites W2143375400 @default.
• W2045337788 cites W2509099452 @default.
• W2045337788 cites W4252485019 @default.
• W2045337788 doi "https://doi.org/10.1016/j.fct.2012.08.007" @default.
• W2045337788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22902823" @default.
• W2045337788 hasPublicationYear "2012" @default.
• W2045337788 type Work @default.
• W2045337788 sameAs 2045337788 @default.
• W2045337788 citedByCount "69" @default.
• W2045337788 countsByYear W20453377882013 @default.
• W2045337788 countsByYear W20453377882014 @default.
• W2045337788 countsByYear W20453377882015 @default.
• W2045337788 countsByYear W20453377882016 @default.
• W2045337788 countsByYear W20453377882017 @default.
• W2045337788 countsByYear W20453377882018 @default.
• W2045337788 countsByYear W20453377882019 @default.
• W2045337788 countsByYear W20453377882020 @default.
• W2045337788 countsByYear W20453377882021 @default.
• W2045337788 countsByYear W20453377882022 @default.
• W2045337788 countsByYear W20453377882023 @default.
• W2045337788 crossrefType "journal-article" @default.
• W2045337788 hasAuthorship W2045337788A5000562106 @default.
• W2045337788 hasAuthorship W2045337788A5001190035 @default.
• W2045337788 hasAuthorship W2045337788A5054123016 @default.
• W2045337788 hasAuthorship W2045337788A5063512998 @default.
• W2045337788 hasConcept C142724271 @default.
• W2045337788 hasConcept C163994747 @default.
• W2045337788 hasConcept C181199279 @default.
• W2045337788 hasConcept C185592680 @default.
• W2045337788 hasConcept C195475562 @default.
• W2045337788 hasConcept C204787440 @default.
• W2045337788 hasConcept C2776080593 @default.
• W2045337788 hasConcept C2778004101 @default.
• W2045337788 hasConcept C2779054382 @default.
• W2045337788 hasConcept C2779532046 @default.
• W2045337788 hasConcept C2780161600 @default.
• W2045337788 hasConcept C2781347565 @default.
• W2045337788 hasConcept C43617362 @default.
• W2045337788 hasConcept C51724486 @default.
• W2045337788 hasConcept C55493867 @default.
• W2045337788 hasConcept C556039675 @default.
• W2045337788 hasConcept C71924100 @default.
• W2045337788 hasConcept C97428945 @default.
• W2045337788 hasConceptScore W2045337788C142724271 @default.
• W2045337788 hasConceptScore W2045337788C163994747 @default.
• W2045337788 hasConceptScore W2045337788C181199279 @default.
• W2045337788 hasConceptScore W2045337788C185592680 @default.
• W2045337788 hasConceptScore W2045337788C195475562 @default.
• W2045337788 hasConceptScore W2045337788C204787440 @default.
• W2045337788 hasConceptScore W2045337788C2776080593 @default.
• W2045337788 hasConceptScore W2045337788C2778004101 @default.
• W2045337788 hasConceptScore W2045337788C2779054382 @default.
• W2045337788 hasConceptScore W2045337788C2779532046 @default.
• W2045337788 hasConceptScore W2045337788C2780161600 @default.
• W2045337788 hasConceptScore W2045337788C2781347565 @default.
• W2045337788 hasConceptScore W2045337788C43617362 @default.
• W2045337788 hasConceptScore W2045337788C51724486 @default.
• W2045337788 hasConceptScore W2045337788C55493867 @default.
• W2045337788 hasConceptScore W2045337788C556039675 @default.
• W2045337788 hasConceptScore W2045337788C71924100 @default.
• W2045337788 hasConceptScore W2045337788C97428945 @default.
• W2045337788 hasIssue "11" @default.
• W2045337788 hasLocation W20453377881 @default.
• W2045337788 hasLocation W20453377882 @default.
• W2045337788 hasOpenAccess W2045337788 @default.
• W2045337788 hasPrimaryLocation W20453377881 @default.
• W2045337788 hasRelatedWork W1820493525 @default.
• W2045337788 hasRelatedWork W2045337788 @default.
• W2045337788 hasRelatedWork W2350271893 @default.
• W2045337788 hasRelatedWork W2359371675 @default.

• next