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• W2045338832 endingPage "1493" @default.
• W2045338832 startingPage "1482" @default.
• W2045338832 abstract "Mitogen-activated protein kinase (MAPK) cascades are important signaling modules in eukaryotic cells. They function downstream of sensors/receptors and regulate cellular responses to external and endogenous stimuli. Recent studies demonstrated that SIPK and WIPK, two tobacco (Nicotiana spp.) MAPKs, are involved in signaling plant defense responses to various pathogens. Ntf4, another tobacco MAPK that shares 93.6% and 72.3% identity with SIPK and WIPK, respectively, was reported to be developmentally regulated and function in pollen germination. We found that Ntf4 is also expressed in leaves and suspension-cultured cells. Genomic analysis excluded the possibility that Ntf4 and SIPK are orthologs from the two parental lines of the amphidiploid common tobacco. In vitro and in vivo phosphorylation and activation assays revealed that Ntf4 shares the same upstream MAPK kinase, NtMEK2, with SIPK and WIPK. Similar to SIPK and WIPK, Ntf4 is also stress responsive and can be activated by cryptogein, a proteinaceous elicitin from oomycetic pathogen Phytophthora cryptogea. Tobacco recognition of cryptogein induces rapid hypersensitive response (HR) cell death in tobacco. Transgenic Ntf4 plants with elevated levels of Ntf4 protein showed accelerated HR cell death when treated with cryptogein. In addition, conditional overexpression of Ntf4, which results in high cellular Ntf4 activity, is sufficient to induce HR-like cell death. Based on these results, we concluded that Ntf4 is multifunctional. In addition to its role in pollen germination, Ntf4 is also a component downstream of NtMEK2 in the MAPK cascade that regulates pathogen-induced HR cell death in tobacco." @default.
• W2045338832 created "2016-06-24" @default.
• W2045338832 creator A5006496385 @default.
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• W2045338832 creator A5067584298 @default.
• W2045338832 creator A5075116238 @default.
• W2045338832 date "2006-06-23" @default.
• W2045338832 modified "2023-10-02" @default.
• W2045338832 title "Activation of Ntf4, a Tobacco Mitogen-Activated Protein Kinase, during Plant Defense Response and Its Involvement in Hypersensitive Response-Like Cell Death" @default.
• W2045338832 cites W1596180848 @default.
• W2045338832 cites W1966725210 @default.
• W2045338832 cites W1968606500 @default.
• W2045338832 cites W1972745413 @default.
• W2045338832 cites W1973328229 @default.
• W2045338832 cites W1973558239 @default.
• W2045338832 cites W1974855449 @default.
• W2045338832 cites W1976385326 @default.
• W2045338832 cites W1978195711 @default.
• W2045338832 cites W1978979107 @default.
• W2045338832 cites W1983316022 @default.
• W2045338832 cites W1987486987 @default.
• W2045338832 cites W1990213589 @default.
• W2045338832 cites W1990921345 @default.
• W2045338832 cites W1993480266 @default.
• W2045338832 cites W1995176042 @default.
• W2045338832 cites W1996405087 @default.
• W2045338832 cites W1997780652 @default.
• W2045338832 cites W2002109416 @default.
• W2045338832 cites W2004689990 @default.
• W2045338832 cites W2008709229 @default.
• W2045338832 cites W2010926562 @default.
• W2045338832 cites W2012930681 @default.
• W2045338832 cites W2017878550 @default.
• W2045338832 cites W2023494247 @default.
• W2045338832 cites W2025265947 @default.
• W2045338832 cites W2025850775 @default.
• W2045338832 cites W2027798995 @default.
• W2045338832 cites W2029503526 @default.
• W2045338832 cites W2040400491 @default.
• W2045338832 cites W2042689385 @default.
• W2045338832 cites W2043161126 @default.
• W2045338832 cites W2043214788 @default.
• W2045338832 cites W2047915557 @default.
• W2045338832 cites W2056924437 @default.
• W2045338832 cites W2066314966 @default.
• W2045338832 cites W2071484587 @default.
• W2045338832 cites W2072655997 @default.
• W2045338832 cites W2075229517 @default.
• W2045338832 cites W2075648225 @default.
• W2045338832 cites W2076485183 @default.
• W2045338832 cites W2078027533 @default.
• W2045338832 cites W2081289101 @default.
• W2045338832 cites W2083117403 @default.
• W2045338832 cites W2085371907 @default.
• W2045338832 cites W2089691429 @default.
• W2045338832 cites W2095058565 @default.
• W2045338832 cites W2095169768 @default.
• W2045338832 cites W2098719212 @default.
• W2045338832 cites W2098837577 @default.
• W2045338832 cites W2100464143 @default.
• W2045338832 cites W2103790202 @default.
• W2045338832 cites W2104941192 @default.
• W2045338832 cites W2109737985 @default.
• W2045338832 cites W2112351234 @default.
• W2045338832 cites W2112945685 @default.
• W2045338832 cites W2120053145 @default.
• W2045338832 cites W2122046489 @default.
• W2045338832 cites W2123769370 @default.
• W2045338832 cites W2125107199 @default.
• W2045338832 cites W2127151407 @default.
• W2045338832 cites W2129742189 @default.
• W2045338832 cites W2129860418 @default.
• W2045338832 cites W2129997424 @default.
• W2045338832 cites W2139163807 @default.
• W2045338832 cites W2147863419 @default.
• W2045338832 cites W2151476068 @default.
• W2045338832 cites W2165205273 @default.
• W2045338832 cites W2165310182 @default.
• W2045338832 cites W2169562034 @default.
• W2045338832 cites W2753607000 @default.
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• W2045338832 doi "https://doi.org/10.1104/pp.106.080697" @default.
• W2045338832 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1533962" @default.
• W2045338832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16798947" @default.
• W2045338832 hasPublicationYear "2006" @default.
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