Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045342519> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2045342519 abstract "The relation between the accumulation of pyrophosphate and technetium-99m in myocardium with reversible and irreversible ischmic injury was studied in dogs subjected to transitory or persistent coronary arterial occlusion. Among four dogs with coronary occlusion maintained for less than 20 minutes, none had either increased MB creatine kinase (CK) (the myocardial CK isoenzyme) activity serum or a positive 99mTc stannous pyrophosphate image. Seven dogs with coronary occlusion maintained for 30 or more minutes had elevated serum MB CK activity, and five of the seven had positive (abnormal) images. Thus, although false negative images may occur occasionally despite myocardial damage, both increased serum MB CK and abnormal images generally accompanied prolonged coronary occlusion. In contrast, ischemia without infarction was not associated with abnormal images. Both 99mTc and 32P labeled pyrophosphate were accumulated extensively and proportionally in myocardium from zones of infarction, and uptake of both tracers was comparable although modest in isolated mitochondria. Similar results were obtained after myocardial infarction in animals with induced profound leukopenia. Thus, phagocytosis of the radiopharmaceutical agent by leukocytes migrating into the infarct is not an essential mechanism accounting for uptake. These results indicate that abnormal images reflect uptake of pyrophosphate, associated with 99mTc, by irreversibly injured myocardium rather than leukocytic infiltration involved in the inflammatory response in the heart." @default.
- W2045342519 created "2016-06-24" @default.
- W2045342519 creator A5027066779 @default.
- W2045342519 creator A5027308245 @default.
- W2045342519 creator A5035615314 @default.
- W2045342519 creator A5051980635 @default.
- W2045342519 creator A5069437161 @default.
- W2045342519 creator A5073599142 @default.
- W2045342519 date "1977-01-01" @default.
- W2045342519 modified "2023-09-26" @default.
- W2045342519 title "Mechanisms contributing to myocardial accumulation of technetium-99m stannous pyrophosphate after coronary arterial occlusion" @default.
- W2045342519 cites W1988211577 @default.
- W2045342519 cites W1994232860 @default.
- W2045342519 cites W1998422536 @default.
- W2045342519 cites W2035710135 @default.
- W2045342519 cites W2036469729 @default.
- W2045342519 cites W2045755758 @default.
- W2045342519 cites W2057822517 @default.
- W2045342519 cites W2068295844 @default.
- W2045342519 cites W2085554856 @default.
- W2045342519 cites W2146918491 @default.
- W2045342519 cites W2341326681 @default.
- W2045342519 cites W2407836082 @default.
- W2045342519 cites W2421306039 @default.
- W2045342519 doi "https://doi.org/10.1016/s0002-9149(77)80011-8" @default.
- W2045342519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/188332" @default.
- W2045342519 hasPublicationYear "1977" @default.
- W2045342519 type Work @default.
- W2045342519 sameAs 2045342519 @default.
- W2045342519 citedByCount "37" @default.
- W2045342519 crossrefType "journal-article" @default.
- W2045342519 hasAuthorship W2045342519A5027066779 @default.
- W2045342519 hasAuthorship W2045342519A5027308245 @default.
- W2045342519 hasAuthorship W2045342519A5035615314 @default.
- W2045342519 hasAuthorship W2045342519A5051980635 @default.
- W2045342519 hasAuthorship W2045342519A5069437161 @default.
- W2045342519 hasAuthorship W2045342519A5073599142 @default.
- W2045342519 hasConcept C126322002 @default.
- W2045342519 hasConcept C164705383 @default.
- W2045342519 hasConcept C181199279 @default.
- W2045342519 hasConcept C185592680 @default.
- W2045342519 hasConcept C2776043855 @default.
- W2045342519 hasConcept C2776268601 @default.
- W2045342519 hasConcept C2777798775 @default.
- W2045342519 hasConcept C2779902710 @default.
- W2045342519 hasConcept C2780393670 @default.
- W2045342519 hasConcept C2989005 @default.
- W2045342519 hasConcept C36880943 @default.
- W2045342519 hasConcept C4375535 @default.
- W2045342519 hasConcept C500558357 @default.
- W2045342519 hasConcept C522557706 @default.
- W2045342519 hasConcept C541997718 @default.
- W2045342519 hasConcept C55493867 @default.
- W2045342519 hasConcept C71924100 @default.
- W2045342519 hasConceptScore W2045342519C126322002 @default.
- W2045342519 hasConceptScore W2045342519C164705383 @default.
- W2045342519 hasConceptScore W2045342519C181199279 @default.
- W2045342519 hasConceptScore W2045342519C185592680 @default.
- W2045342519 hasConceptScore W2045342519C2776043855 @default.
- W2045342519 hasConceptScore W2045342519C2776268601 @default.
- W2045342519 hasConceptScore W2045342519C2777798775 @default.
- W2045342519 hasConceptScore W2045342519C2779902710 @default.
- W2045342519 hasConceptScore W2045342519C2780393670 @default.
- W2045342519 hasConceptScore W2045342519C2989005 @default.
- W2045342519 hasConceptScore W2045342519C36880943 @default.
- W2045342519 hasConceptScore W2045342519C4375535 @default.
- W2045342519 hasConceptScore W2045342519C500558357 @default.
- W2045342519 hasConceptScore W2045342519C522557706 @default.
- W2045342519 hasConceptScore W2045342519C541997718 @default.
- W2045342519 hasConceptScore W2045342519C55493867 @default.
- W2045342519 hasConceptScore W2045342519C71924100 @default.
- W2045342519 hasLocation W20453425191 @default.
- W2045342519 hasLocation W20453425192 @default.
- W2045342519 hasOpenAccess W2045342519 @default.
- W2045342519 hasPrimaryLocation W20453425191 @default.
- W2045342519 hasRelatedWork W2041050824 @default.
- W2045342519 hasRelatedWork W2045342519 @default.
- W2045342519 hasRelatedWork W2085567467 @default.
- W2045342519 hasRelatedWork W2104613067 @default.
- W2045342519 hasRelatedWork W2144617865 @default.
- W2045342519 hasRelatedWork W2347107582 @default.
- W2045342519 hasRelatedWork W2402639938 @default.
- W2045342519 hasRelatedWork W72230356 @default.
- W2045342519 hasRelatedWork W93085525 @default.
- W2045342519 hasRelatedWork W2040806735 @default.
- W2045342519 isParatext "false" @default.
- W2045342519 isRetracted "false" @default.
- W2045342519 magId "2045342519" @default.
- W2045342519 workType "article" @default.