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• W2045343248 startingPage "116" @default.
• W2045343248 abstract "Eccentric muscle contractions such as those experienced during downhill running are associated with inflammation, delayed-onset of muscle soreness, myofiber damage, and various functional deficits. North American ginseng (Panax quinquefolius L.) has been reported to possess anti-inflammatory properties and thus may offset some of this exercise-induced damage. Hence, we tested the hypothesis that intervention with North American ginseng would reduce eccentric exercise-induced muscle damage and inflammation. Male Wistar rats were fed (300 mg/(kg·day) –1 ) of either an alcohol (AL) or aqueous (AQ) extract of North American ginseng for 14 days before a single bout of downhill running and were compared with matching nonexercised (C) groups. Plasma creatine kinase levels were significantly reduced in both ginseng treated groups compared with the C group that received a water placebo (p < 0.002). Further, the AQ but not AL group also showed attenuated morphological signs of damage (hemotoxylin and eosin) as well as reduced levels of infiltrating neutrophils (HIS48) in the soleus muscle (p < 0.001). In summary, supplementation with an AQ but not AL extract of North American ginseng was able to reduce eccentric exercise-induced muscle damage and inflammation." @default.
• W2045343248 created "2016-06-24" @default.
• W2045343248 creator A5002125692 @default.
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• W2045343248 date "2015-02-01" @default.
• W2045343248 modified "2023-10-18" @default.
• W2045343248 title "North American ginseng protects against muscle damage and reduces neutrophil infiltration after an acute bout of downhill running in rats" @default.
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• W2045343248 doi "https://doi.org/10.1139/apnm-2014-0331" @default.
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