Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045344512> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2045344512 endingPage "2054" @default.
- W2045344512 startingPage "2051" @default.
- W2045344512 abstract "Adenosine A2A, group I mGlu and neurotensin receptors have been previously found to modulate the binding characteristics of dopamine D2 receptors in membrane preparations from rat striatum. In the present study it is shown that stimulation of different combinations of striatal A2A, group I mGlu and neurotensin receptors induce different effects on the modulation of D2 receptor binding to those obtained when they are separately stimulated using maximal effective concentrations. In competitive inhibition experiments of dopamine versus the D2 receptor antagonist [3H]raclopride the addition of the A2A receptor agonist CGS 21680, the group I mGlu receptor agonist DHPG or neurotensin induced a decrease in the affinity of the high affinity state of the dopamine D2 receptors for dopamine. When added together CGS 21680 plus neurotensin induced the same effect as when administered alone, CGS 21680 plus DHPG induced a synergistic effect and DHPG plus neurotensin lost their modulating effect on D2 receptor binding. These results demonstrate the existence of multiple intramembrane receptor-receptor interactions in the regulation of striatal D2 receptors." @default.
- W2045344512 created "2016-06-24" @default.
- W2045344512 creator A5000524771 @default.
- W2045344512 creator A5048458525 @default.
- W2045344512 creator A5090577395 @default.
- W2045344512 date "1999-07-01" @default.
- W2045344512 modified "2023-10-17" @default.
- W2045344512 title "Multiple intramembrane receptor–receptor interactions in the regulation of striatal dopamine D2 receptors" @default.
- W2045344512 cites W1983108892 @default.
- W2045344512 cites W2014477753 @default.
- W2045344512 cites W2015759121 @default.
- W2045344512 cites W2041619785 @default.
- W2045344512 doi "https://doi.org/10.1097/00001756-199907130-00011" @default.
- W2045344512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10424673" @default.
- W2045344512 hasPublicationYear "1999" @default.
- W2045344512 type Work @default.
- W2045344512 sameAs 2045344512 @default.
- W2045344512 citedByCount "20" @default.
- W2045344512 countsByYear W20453445122012 @default.
- W2045344512 countsByYear W20453445122016 @default.
- W2045344512 countsByYear W20453445122019 @default.
- W2045344512 countsByYear W20453445122020 @default.
- W2045344512 crossrefType "journal-article" @default.
- W2045344512 hasAuthorship W2045344512A5000524771 @default.
- W2045344512 hasAuthorship W2045344512A5048458525 @default.
- W2045344512 hasAuthorship W2045344512A5090577395 @default.
- W2045344512 hasConcept C118303440 @default.
- W2045344512 hasConcept C120069818 @default.
- W2045344512 hasConcept C120750228 @default.
- W2045344512 hasConcept C126322002 @default.
- W2045344512 hasConcept C134018914 @default.
- W2045344512 hasConcept C160262196 @default.
- W2045344512 hasConcept C170493617 @default.
- W2045344512 hasConcept C185592680 @default.
- W2045344512 hasConcept C2777307743 @default.
- W2045344512 hasConcept C2778938600 @default.
- W2045344512 hasConcept C2778976297 @default.
- W2045344512 hasConcept C2780231331 @default.
- W2045344512 hasConcept C2781069445 @default.
- W2045344512 hasConcept C44208683 @default.
- W2045344512 hasConcept C513476851 @default.
- W2045344512 hasConcept C67907053 @default.
- W2045344512 hasConcept C71924100 @default.
- W2045344512 hasConcept C86803240 @default.
- W2045344512 hasConcept C98274493 @default.
- W2045344512 hasConceptScore W2045344512C118303440 @default.
- W2045344512 hasConceptScore W2045344512C120069818 @default.
- W2045344512 hasConceptScore W2045344512C120750228 @default.
- W2045344512 hasConceptScore W2045344512C126322002 @default.
- W2045344512 hasConceptScore W2045344512C134018914 @default.
- W2045344512 hasConceptScore W2045344512C160262196 @default.
- W2045344512 hasConceptScore W2045344512C170493617 @default.
- W2045344512 hasConceptScore W2045344512C185592680 @default.
- W2045344512 hasConceptScore W2045344512C2777307743 @default.
- W2045344512 hasConceptScore W2045344512C2778938600 @default.
- W2045344512 hasConceptScore W2045344512C2778976297 @default.
- W2045344512 hasConceptScore W2045344512C2780231331 @default.
- W2045344512 hasConceptScore W2045344512C2781069445 @default.
- W2045344512 hasConceptScore W2045344512C44208683 @default.
- W2045344512 hasConceptScore W2045344512C513476851 @default.
- W2045344512 hasConceptScore W2045344512C67907053 @default.
- W2045344512 hasConceptScore W2045344512C71924100 @default.
- W2045344512 hasConceptScore W2045344512C86803240 @default.
- W2045344512 hasConceptScore W2045344512C98274493 @default.
- W2045344512 hasIssue "10" @default.
- W2045344512 hasLocation W20453445121 @default.
- W2045344512 hasLocation W20453445122 @default.
- W2045344512 hasOpenAccess W2045344512 @default.
- W2045344512 hasPrimaryLocation W20453445121 @default.
- W2045344512 hasRelatedWork W1976603775 @default.
- W2045344512 hasRelatedWork W1979792701 @default.
- W2045344512 hasRelatedWork W2008135839 @default.
- W2045344512 hasRelatedWork W2028161731 @default.
- W2045344512 hasRelatedWork W2044431854 @default.
- W2045344512 hasRelatedWork W2045344512 @default.
- W2045344512 hasRelatedWork W2063944612 @default.
- W2045344512 hasRelatedWork W2071328884 @default.
- W2045344512 hasRelatedWork W2073811833 @default.
- W2045344512 hasRelatedWork W2081857759 @default.
- W2045344512 hasVolume "10" @default.
- W2045344512 isParatext "false" @default.
- W2045344512 isRetracted "false" @default.
- W2045344512 magId "2045344512" @default.
- W2045344512 workType "article" @default.