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- W2045348392 abstract "Within the past 5 years, the synthesis and biological evaluations of organosilicon agents have rapidly developed into a potentially explosive area of medicinal chemistry. It has repeatedly been demonstrated that silicon analogs of recognized medicinal agents exhibit biological activity. Even more significant is the activity elicited by several types of organosilicon entities that are not isosteric to biologically active organic compounds. Ample evidence is also now available to establish that organosilicon compounds, per se, are not toxic. While certain classes of these compounds produce toxic responses, indeed, a few are highly poisonous, they too are not merely silicon congeners of toxic organic compounds. The diverse employment of these compounds—from therapeutic agents to agricultural chemicals—evidences the importance of, and exceptional potential for, these materials." @default.
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- W2045348392 date "1971-08-01" @default.
- W2045348392 modified "2023-10-12" @default.
- W2045348392 title "Organosilicon Entities as Prophylactic and Therapeutic Agents" @default.
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- W2045348392 doi "https://doi.org/10.1002/jps.2600600802" @default.
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