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- W2045348533 abstract "Well structured: As a new triose phosphate isomerase (TIM) barrel-fold prenyl transferase, PcrB catalyzes the production of heptaprenylglyceryl phosphate from heptaprenyl diphosphate and glycerol-1-phosphate. Crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus in complex with ligands were solved, and together with site-directed mutagenesis and bioinformatics analyses, clearly reveal the catalytic mechanism of the enzyme." @default.
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- W2045348533 date "2013-01-15" @default.
- W2045348533 modified "2023-10-07" @default.
- W2045348533 title "Insights into TIM-Barrel Prenyl Transferase Mechanisms: Crystal Structures of PcrB from<i>Bacillus subtilis</i>and<i>Staphylococcus aureus</i>" @default.
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- W2045348533 doi "https://doi.org/10.1002/cbic.201200748" @default.
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