Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045352502> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2045352502 endingPage "23" @default.
- W2045352502 startingPage "19" @default.
- W2045352502 abstract "The effects of a new anticonvulsive derivative of taurine, taltrimide (2-phthalimido-ethanesulphon-N-isopropylamide), and its metabolites on the release, uptake and binding of gamma-aminobutyric acid (GABA) and taurine, were studied in the cerebrum of the mouse. The potassium-stimulated release of taurine from slices of cerebral cortex was inhibited in vitro by taltrimide and its dealkylated metabolite, whereas the stimulated release of GABA was significantly enhanced by both drugs. The uptake of taurine and GABA were not markedly affected. Both taltrimide and its dealkylated metabolite strongly inhibited the sodium-independent binding of taurine to synaptic membranes of brain, the effects on the binding of GABA being less pronounced. The actions on synaptic binding of taurine and on depolarization-stimulated release of GABA may be of significance for their anticonvulsant properties." @default.
- W2045352502 created "2016-06-24" @default.
- W2045352502 creator A5042573079 @default.
- W2045352502 creator A5077732291 @default.
- W2045352502 date "1987-01-01" @default.
- W2045352502 modified "2023-09-27" @default.
- W2045352502 title "Effects of the anticonvulsant taurine derivative, taltrimide, on membrane transport and binding of GABA and taurine in the mouse cerebrum" @default.
- W2045352502 cites W1965274170 @default.
- W2045352502 cites W1975606880 @default.
- W2045352502 cites W1982312847 @default.
- W2045352502 cites W1985691175 @default.
- W2045352502 cites W2001251363 @default.
- W2045352502 cites W2013155661 @default.
- W2045352502 cites W2022771278 @default.
- W2045352502 cites W2033376304 @default.
- W2045352502 cites W2043110735 @default.
- W2045352502 cites W2053819855 @default.
- W2045352502 cites W2058305592 @default.
- W2045352502 cites W2060014260 @default.
- W2045352502 cites W2062360095 @default.
- W2045352502 cites W2070699524 @default.
- W2045352502 cites W2072331922 @default.
- W2045352502 cites W2082470658 @default.
- W2045352502 cites W2088136923 @default.
- W2045352502 cites W2088439750 @default.
- W2045352502 cites W2149757306 @default.
- W2045352502 cites W4236316486 @default.
- W2045352502 doi "https://doi.org/10.1016/0028-3908(87)90039-6" @default.
- W2045352502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3031533" @default.
- W2045352502 hasPublicationYear "1987" @default.
- W2045352502 type Work @default.
- W2045352502 sameAs 2045352502 @default.
- W2045352502 citedByCount "24" @default.
- W2045352502 countsByYear W20453525022012 @default.
- W2045352502 countsByYear W20453525022013 @default.
- W2045352502 countsByYear W20453525022015 @default.
- W2045352502 countsByYear W20453525022019 @default.
- W2045352502 crossrefType "journal-article" @default.
- W2045352502 hasAuthorship W2045352502A5042573079 @default.
- W2045352502 hasAuthorship W2045352502A5077732291 @default.
- W2045352502 hasConcept C134018914 @default.
- W2045352502 hasConcept C169760540 @default.
- W2045352502 hasConcept C185592680 @default.
- W2045352502 hasConcept C2775858608 @default.
- W2045352502 hasConcept C2777477808 @default.
- W2045352502 hasConcept C2778186239 @default.
- W2045352502 hasConcept C2779701627 @default.
- W2045352502 hasConcept C515207424 @default.
- W2045352502 hasConcept C529278444 @default.
- W2045352502 hasConcept C533869091 @default.
- W2045352502 hasConcept C55493867 @default.
- W2045352502 hasConcept C86803240 @default.
- W2045352502 hasConcept C98274493 @default.
- W2045352502 hasConceptScore W2045352502C134018914 @default.
- W2045352502 hasConceptScore W2045352502C169760540 @default.
- W2045352502 hasConceptScore W2045352502C185592680 @default.
- W2045352502 hasConceptScore W2045352502C2775858608 @default.
- W2045352502 hasConceptScore W2045352502C2777477808 @default.
- W2045352502 hasConceptScore W2045352502C2778186239 @default.
- W2045352502 hasConceptScore W2045352502C2779701627 @default.
- W2045352502 hasConceptScore W2045352502C515207424 @default.
- W2045352502 hasConceptScore W2045352502C529278444 @default.
- W2045352502 hasConceptScore W2045352502C533869091 @default.
- W2045352502 hasConceptScore W2045352502C55493867 @default.
- W2045352502 hasConceptScore W2045352502C86803240 @default.
- W2045352502 hasConceptScore W2045352502C98274493 @default.
- W2045352502 hasIssue "1" @default.
- W2045352502 hasLocation W20453525021 @default.
- W2045352502 hasLocation W20453525022 @default.
- W2045352502 hasOpenAccess W2045352502 @default.
- W2045352502 hasPrimaryLocation W20453525021 @default.
- W2045352502 hasRelatedWork W1964759623 @default.
- W2045352502 hasRelatedWork W2027216937 @default.
- W2045352502 hasRelatedWork W2045352502 @default.
- W2045352502 hasRelatedWork W2057547792 @default.
- W2045352502 hasRelatedWork W2064648180 @default.
- W2045352502 hasRelatedWork W2066723852 @default.
- W2045352502 hasRelatedWork W2076009449 @default.
- W2045352502 hasRelatedWork W2082470658 @default.
- W2045352502 hasRelatedWork W2943405303 @default.
- W2045352502 hasRelatedWork W2970770038 @default.
- W2045352502 hasVolume "26" @default.
- W2045352502 isParatext "false" @default.
- W2045352502 isRetracted "false" @default.
- W2045352502 magId "2045352502" @default.
- W2045352502 workType "article" @default.