Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045365093> ?p ?o ?g. }
- W2045365093 endingPage "709" @default.
- W2045365093 startingPage "701" @default.
- W2045365093 abstract "Compounds naturally occurring in plants and animals play an essential role in the prevention and treatment of various cancers. There are more than 100 plant- and animal-based natural compounds currently in clinical use. Similar to synthetic compounds, these natural compounds are associated with dose-related toxicity that limits efficacy. Scientists have investigated combination therapy with compounds that have different toxicities in order to optimize efficacy. These combination therapies may work additively or synergistically, there may be no effect or they may promote tumor formation. Combination therapy with agents that have similar mechanisms of action may increase toxicity. In this article, combination therapies that have been investigated, their rationale, mechanism of action and findings are reviewed. When the data warrant it, combined (pharmacologic and natural; two or more natural) interventions that appear to increase efficacy (compared with monotherapy) while minimizing toxicity have been highlighted." @default.
- W2045365093 created "2016-06-24" @default.
- W2045365093 creator A5019458232 @default.
- W2045365093 creator A5043556576 @default.
- W2045365093 date "2012-11-01" @default.
- W2045365093 modified "2023-09-25" @default.
- W2045365093 title "Cancer prevention and treatment using combination therapy with plant- and animal-derived compounds" @default.
- W2045365093 cites W1856177890 @default.
- W2045365093 cites W1965300148 @default.
- W2045365093 cites W1972199783 @default.
- W2045365093 cites W1977739939 @default.
- W2045365093 cites W1978283158 @default.
- W2045365093 cites W1984283228 @default.
- W2045365093 cites W1984313874 @default.
- W2045365093 cites W1984846756 @default.
- W2045365093 cites W1985374049 @default.
- W2045365093 cites W1986482685 @default.
- W2045365093 cites W1987740582 @default.
- W2045365093 cites W1989852705 @default.
- W2045365093 cites W1996721832 @default.
- W2045365093 cites W1998887711 @default.
- W2045365093 cites W2000178617 @default.
- W2045365093 cites W2000267962 @default.
- W2045365093 cites W2000732112 @default.
- W2045365093 cites W2001094711 @default.
- W2045365093 cites W2001779498 @default.
- W2045365093 cites W2002587733 @default.
- W2045365093 cites W2008838407 @default.
- W2045365093 cites W2011608085 @default.
- W2045365093 cites W2012136540 @default.
- W2045365093 cites W2013038015 @default.
- W2045365093 cites W2013738718 @default.
- W2045365093 cites W2015187968 @default.
- W2045365093 cites W2021268614 @default.
- W2045365093 cites W2025221196 @default.
- W2045365093 cites W2026644677 @default.
- W2045365093 cites W2026722740 @default.
- W2045365093 cites W2028646638 @default.
- W2045365093 cites W2029085730 @default.
- W2045365093 cites W2030139358 @default.
- W2045365093 cites W2031187947 @default.
- W2045365093 cites W2036280036 @default.
- W2045365093 cites W2039856508 @default.
- W2045365093 cites W2046303440 @default.
- W2045365093 cites W2048580007 @default.
- W2045365093 cites W2049178173 @default.
- W2045365093 cites W2050837407 @default.
- W2045365093 cites W2051908102 @default.
- W2045365093 cites W2058717279 @default.
- W2045365093 cites W2071437559 @default.
- W2045365093 cites W2072644819 @default.
- W2045365093 cites W2074347967 @default.
- W2045365093 cites W2078682475 @default.
- W2045365093 cites W2081976043 @default.
- W2045365093 cites W2082647619 @default.
- W2045365093 cites W2092874597 @default.
- W2045365093 cites W2094142092 @default.
- W2045365093 cites W2094292815 @default.
- W2045365093 cites W2101213151 @default.
- W2045365093 cites W2102271210 @default.
- W2045365093 cites W2103023937 @default.
- W2045365093 cites W2106136082 @default.
- W2045365093 cites W2109858742 @default.
- W2045365093 cites W2111396140 @default.
- W2045365093 cites W2113920410 @default.
- W2045365093 cites W2117958397 @default.
- W2045365093 cites W2119331100 @default.
- W2045365093 cites W2119880272 @default.
- W2045365093 cites W2120568689 @default.
- W2045365093 cites W2122967659 @default.
- W2045365093 cites W2131264460 @default.
- W2045365093 cites W2136679865 @default.
- W2045365093 cites W2141958178 @default.
- W2045365093 cites W2143289308 @default.
- W2045365093 cites W2150088024 @default.
- W2045365093 cites W2151089147 @default.
- W2045365093 cites W2151300092 @default.
- W2045365093 cites W2153524297 @default.
- W2045365093 cites W2160400857 @default.
- W2045365093 cites W2162139093 @default.
- W2045365093 cites W2166549828 @default.
- W2045365093 cites W2167060703 @default.
- W2045365093 cites W2170642071 @default.
- W2045365093 cites W248512158 @default.
- W2045365093 cites W2764451377 @default.
- W2045365093 cites W4236890185 @default.
- W2045365093 doi "https://doi.org/10.1586/ecp.12.62" @default.
- W2045365093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23234327" @default.
- W2045365093 hasPublicationYear "2012" @default.
- W2045365093 type Work @default.
- W2045365093 sameAs 2045365093 @default.
- W2045365093 citedByCount "22" @default.
- W2045365093 countsByYear W20453650932013 @default.
- W2045365093 countsByYear W20453650932014 @default.
- W2045365093 countsByYear W20453650932015 @default.
- W2045365093 countsByYear W20453650932016 @default.
- W2045365093 countsByYear W20453650932017 @default.
- W2045365093 countsByYear W20453650932018 @default.