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• W2045374148 abstract "Copolymers of N-(2-hydroxypropyl)methacrylamide were prepared, in which synthetic polymer chains are joined by crosslinks containing oligopeptidic sequences degradable with papain, with the general structure P-(Gly)nX-Y-NH-(CH2)66-NH-Y-X-(Gly)n-P (Pisthepolymerchain, n = 1, 2; X…Phe, Val, Gly;Y... Lys, Gly, Tyr, Ala, Phe). The relationship between the structure of these polymeric substrates and their degradability with papain was investigated viscometrically. It was shown that -Phe-Lys- was the most suitable -X-Y- sequence. Extension of the oligopeptidic sequence by one amino acid residue causes a pronounced rise in the rate of cleavage of the polymeric substrates." @default.
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• W2045374148 date "1980-10-01" @default.
• W2045374148 modified "2023-10-03" @default.
• W2045374148 title "Polymers containing enzymatically degradable bonds V. Hydrophilic polymers degradable by papain" @default.
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• W2045374148 doi "https://doi.org/10.1016/0142-9612(80)90017-4" @default.
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