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- W2045390886 abstract "The genetic basis of attenuation of the poliovirus type 3 vaccine strain P3/Leon 12a1b has been investigated by comparing the nucleotide sequence of this strain with that of its neurovirulent progenitor P3/Leon/37 and by constructing recombinants between these two viruses using infectious cDNAs. Preliminary results suggest that attenuation is caused by just two point mutations, one occurring in the 5' non-coding region and the other causing an amino acid change in coat protein VP3." @default.
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- W2045390886 date "1987-08-01" @default.
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- W2045390886 title "Studies on the attenuation of the Sabin type 3 oral polio vaccine" @default.
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- W2045390886 doi "https://doi.org/10.1016/0166-0934(87)90081-4" @default.
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