FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045392933> ?p ?o ?g. }

• W2045392933 endingPage "904" @default.
• W2045392933 startingPage "898" @default.
• W2045392933 abstract "ADAM33 is the first identified asthma gene by positional cloning, especially asthma combined with bronchial hyperresponsiveness (BHR). Moreover, ADAM33 is associated with early-life lung function and decline of forced expiratory volume in 1 s (FEV(1)) in the general population. In utero and postnatal cigarette smoke exposure (CSE) are associated with reduced lung function, and development of BHR and asthma. We hypothesized that this may occur via interaction with ADAM33.To replicate the role of ADAM33 in childhood lung function and development of BHR and asthma. Furthermore, we investigated gene-environment interaction of ADAM33 with in utero and postnatal CSE in the Dutch PIAMA cohort.Six ADAM33 single-nucleotide polymorphisms (SNPs) were genotyped. Rint was measured at age 4 and 8 years, FEV(1) and BHR at age 8 years; asthma was based on questionnaire data at age 8.In the total cohort, the rs511898 A, rs528557 C, and rs2280090 A alleles increased the risk to develop asthma (+BHR). There existed interaction between in utero but not postnatal CSE and the rs528557 and rs3918396 SNPs with respect to development of BHR, the rs3918396 SNP with Rint at age 8 and the rs528557 SNP with FEV(1)% predicted.We confirm associations between ADAM33 and the development of asthma (+BHR). This is the first study suggesting that interaction of in utero CSE with ADAM33 results in reduced lung function and the development of BHR, which needs further confirmation." @default.
• W2045392933 created "2016-06-24" @default.
• W2045392933 creator A5012222426 @default.
• W2045392933 creator A5019379466 @default.
• W2045392933 creator A5025017022 @default.
• W2045392933 creator A5026205015 @default.
• W2045392933 creator A5030603878 @default.
• W2045392933 creator A5041829694 @default.
• W2045392933 creator A5049893668 @default.
• W2045392933 creator A5081381348 @default.
• W2045392933 date "2009-06-01" @default.
• W2045392933 modified "2023-10-10" @default.
• W2045392933 title "Smoke exposure interacts with<i>ADAM33</i>polymorphisms in the development of lung function and hyperresponsiveness" @default.
• W2045392933 cites W1786542967 @default.
• W2045392933 cites W1908187481 @default.
• W2045392933 cites W1977441406 @default.
• W2045392933 cites W1991029998 @default.
• W2045392933 cites W1994101077 @default.
• W2045392933 cites W2033425349 @default.
• W2045392933 cites W2034662757 @default.
• W2045392933 cites W2036615072 @default.
• W2045392933 cites W2041373197 @default.
• W2045392933 cites W2044123048 @default.
• W2045392933 cites W2045832454 @default.
• W2045392933 cites W2063014521 @default.
• W2045392933 cites W2063317751 @default.
• W2045392933 cites W2075139637 @default.
• W2045392933 cites W2075278891 @default.
• W2045392933 cites W2093527897 @default.
• W2045392933 cites W2108712187 @default.
• W2045392933 cites W2111657314 @default.
• W2045392933 cites W2113966843 @default.
• W2045392933 cites W2114554839 @default.
• W2045392933 cites W2117263999 @default.
• W2045392933 cites W2118295394 @default.
• W2045392933 cites W2120006832 @default.
• W2045392933 cites W2130784530 @default.
• W2045392933 cites W2132569024 @default.
• W2045392933 cites W2135171274 @default.
• W2045392933 cites W2139973059 @default.
• W2045392933 cites W2140091208 @default.
• W2045392933 cites W2146374576 @default.
• W2045392933 cites W2147808314 @default.
• W2045392933 cites W2147815892 @default.
• W2045392933 cites W2154395112 @default.
• W2045392933 cites W2159874728 @default.
• W2045392933 cites W2161366264 @default.
• W2045392933 cites W2166226439 @default.
• W2045392933 doi "https://doi.org/10.1111/j.1398-9995.2009.01939.x" @default.
• W2045392933 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19236319" @default.
• W2045392933 hasPublicationYear "2009" @default.
• W2045392933 type Work @default.
• W2045392933 sameAs 2045392933 @default.
• W2045392933 citedByCount "50" @default.
• W2045392933 countsByYear W20453929332012 @default.
• W2045392933 countsByYear W20453929332013 @default.
• W2045392933 countsByYear W20453929332014 @default.
• W2045392933 countsByYear W20453929332015 @default.
• W2045392933 countsByYear W20453929332016 @default.
• W2045392933 countsByYear W20453929332017 @default.
• W2045392933 countsByYear W20453929332018 @default.
• W2045392933 countsByYear W20453929332019 @default.
• W2045392933 countsByYear W20453929332021 @default.
• W2045392933 crossrefType "journal-article" @default.
• W2045392933 hasAuthorship W2045392933A5012222426 @default.
• W2045392933 hasAuthorship W2045392933A5019379466 @default.
• W2045392933 hasAuthorship W2045392933A5025017022 @default.
• W2045392933 hasAuthorship W2045392933A5026205015 @default.
• W2045392933 hasAuthorship W2045392933A5030603878 @default.
• W2045392933 hasAuthorship W2045392933A5041829694 @default.
• W2045392933 hasAuthorship W2045392933A5049893668 @default.
• W2045392933 hasAuthorship W2045392933A5081381348 @default.
• W2045392933 hasConcept C104317684 @default.
• W2045392933 hasConcept C126322002 @default.
• W2045392933 hasConcept C135763542 @default.
• W2045392933 hasConcept C139275648 @default.
• W2045392933 hasConcept C153209595 @default.
• W2045392933 hasConcept C172680121 @default.
• W2045392933 hasConcept C201614185 @default.
• W2045392933 hasConcept C203014093 @default.
• W2045392933 hasConcept C2776042228 @default.
• W2045392933 hasConcept C2776178081 @default.
• W2045392933 hasConcept C2776238763 @default.
• W2045392933 hasConcept C2777714996 @default.
• W2045392933 hasConcept C2778355491 @default.
• W2045392933 hasConcept C2779234561 @default.
• W2045392933 hasConcept C54355233 @default.
• W2045392933 hasConcept C71924100 @default.
• W2045392933 hasConcept C72563966 @default.
• W2045392933 hasConcept C86803240 @default.
• W2045392933 hasConcept C99454951 @default.
• W2045392933 hasConceptScore W2045392933C104317684 @default.
• W2045392933 hasConceptScore W2045392933C126322002 @default.
• W2045392933 hasConceptScore W2045392933C135763542 @default.
• W2045392933 hasConceptScore W2045392933C139275648 @default.
• W2045392933 hasConceptScore W2045392933C153209595 @default.
• W2045392933 hasConceptScore W2045392933C172680121 @default.
• W2045392933 hasConceptScore W2045392933C201614185 @default.

• next