Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045401072> ?p ?o ?g. }
- W2045401072 endingPage "1176" @default.
- W2045401072 startingPage "1169" @default.
- W2045401072 abstract "Cell-derived procoagulant microparticles (MP) might be able to contribute to exercise-induced changes in blood hemostasis.This study aimed to examine (i) the concentration and procoagulant activity of cell-derived MP after a moderate endurance exercise and (ii) the differences in the release, clearance, and activity of MP before and after exercise between trained and untrained individuals.All subjects performed a single bout of physical exercise on a bicycle ergometer for 90 min at 80% of their individual anaerobic threshold. MP were identified and quantified by flow cytometry measurements. Procoagulant activity of MP was measured by a prothrombinase activity assay as well as tissue factor-induced fibrin formation in MP-containing plasma.At baseline, no differences were observed for the absolute number and procoagulant activities of MP between trained and untrained subjects. However, trained individuals had a lower number of tissue factor-positive monocyte-derived MP compared with untrained individuals. In trained subjects, exercise induced a significant increase in the number of MP derived from platelets, monocytes, and endothelial cells, with maximum values at 45 min after exercise and returned to basal levels at 2 h after exercise. Untrained subjects revealed a similar increase in platelet-derived MP, but their level was still increased at 2 h after exercise, indicating a reduced clearance compared with trained individuals. Procoagulant activities of MP were increased immediately after exercise and remained elevated up to 2 h after exercise.We conclude that increased levels of MP were found in healthy individuals after an acute bout of exercise, that the amount of circulating MP contributes to an exercise-induced increase of hemostatic potential, and that there were differences in kinetic and dynamic characteristics between trained and untrained individuals." @default.
- W2045401072 created "2016-06-24" @default.
- W2045401072 creator A5036283063 @default.
- W2045401072 creator A5049712910 @default.
- W2045401072 creator A5057771610 @default.
- W2045401072 creator A5080542418 @default.
- W2045401072 creator A5089601662 @default.
- W2045401072 date "2011-07-01" @default.
- W2045401072 modified "2023-09-30" @default.
- W2045401072 title "Cell-Derived Microparticles Promote Coagulation after Moderate Exercise" @default.
- W2045401072 cites W1067657432 @default.
- W2045401072 cites W113835883 @default.
- W2045401072 cites W1727122499 @default.
- W2045401072 cites W1973340784 @default.
- W2045401072 cites W1977208217 @default.
- W2045401072 cites W1978588384 @default.
- W2045401072 cites W1980187848 @default.
- W2045401072 cites W1985400269 @default.
- W2045401072 cites W2009556518 @default.
- W2045401072 cites W2017269547 @default.
- W2045401072 cites W2020592012 @default.
- W2045401072 cites W2031336341 @default.
- W2045401072 cites W2046149998 @default.
- W2045401072 cites W2065890514 @default.
- W2045401072 cites W2067279383 @default.
- W2045401072 cites W2069552970 @default.
- W2045401072 cites W2076661911 @default.
- W2045401072 cites W2077049963 @default.
- W2045401072 cites W2077088741 @default.
- W2045401072 cites W2079949057 @default.
- W2045401072 cites W2080314410 @default.
- W2045401072 cites W2092632463 @default.
- W2045401072 cites W2093495812 @default.
- W2045401072 cites W2095793217 @default.
- W2045401072 cites W2102453345 @default.
- W2045401072 cites W2104232901 @default.
- W2045401072 cites W2110463923 @default.
- W2045401072 cites W2114034523 @default.
- W2045401072 cites W2114495365 @default.
- W2045401072 cites W2129772120 @default.
- W2045401072 cites W2140527652 @default.
- W2045401072 cites W2142126156 @default.
- W2045401072 cites W2153696888 @default.
- W2045401072 cites W2156877554 @default.
- W2045401072 cites W2172278128 @default.
- W2045401072 cites W2917017869 @default.
- W2045401072 doi "https://doi.org/10.1249/mss.0b013e3182068645" @default.
- W2045401072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21131870" @default.
- W2045401072 hasPublicationYear "2011" @default.
- W2045401072 type Work @default.
- W2045401072 sameAs 2045401072 @default.
- W2045401072 citedByCount "66" @default.
- W2045401072 countsByYear W20454010722012 @default.
- W2045401072 countsByYear W20454010722013 @default.
- W2045401072 countsByYear W20454010722014 @default.
- W2045401072 countsByYear W20454010722015 @default.
- W2045401072 countsByYear W20454010722016 @default.
- W2045401072 countsByYear W20454010722017 @default.
- W2045401072 countsByYear W20454010722018 @default.
- W2045401072 countsByYear W20454010722019 @default.
- W2045401072 countsByYear W20454010722020 @default.
- W2045401072 countsByYear W20454010722021 @default.
- W2045401072 countsByYear W20454010722022 @default.
- W2045401072 countsByYear W20454010722023 @default.
- W2045401072 crossrefType "journal-article" @default.
- W2045401072 hasAuthorship W2045401072A5036283063 @default.
- W2045401072 hasAuthorship W2045401072A5049712910 @default.
- W2045401072 hasAuthorship W2045401072A5057771610 @default.
- W2045401072 hasAuthorship W2045401072A5080542418 @default.
- W2045401072 hasAuthorship W2045401072A5089601662 @default.
- W2045401072 hasBestOaLocation W20454010721 @default.
- W2045401072 hasConcept C112516734 @default.
- W2045401072 hasConcept C126322002 @default.
- W2045401072 hasConcept C134018914 @default.
- W2045401072 hasConcept C181588539 @default.
- W2045401072 hasConcept C185592680 @default.
- W2045401072 hasConcept C1862650 @default.
- W2045401072 hasConcept C186738567 @default.
- W2045401072 hasConcept C203014093 @default.
- W2045401072 hasConcept C2777292125 @default.
- W2045401072 hasConcept C2778024521 @default.
- W2045401072 hasConcept C2778382381 @default.
- W2045401072 hasConcept C2778589496 @default.
- W2045401072 hasConcept C2779306644 @default.
- W2045401072 hasConcept C5140985 @default.
- W2045401072 hasConcept C553184892 @default.
- W2045401072 hasConcept C71924100 @default.
- W2045401072 hasConcept C89560881 @default.
- W2045401072 hasConcept C99830354 @default.
- W2045401072 hasConceptScore W2045401072C112516734 @default.
- W2045401072 hasConceptScore W2045401072C126322002 @default.
- W2045401072 hasConceptScore W2045401072C134018914 @default.
- W2045401072 hasConceptScore W2045401072C181588539 @default.
- W2045401072 hasConceptScore W2045401072C185592680 @default.
- W2045401072 hasConceptScore W2045401072C1862650 @default.
- W2045401072 hasConceptScore W2045401072C186738567 @default.
- W2045401072 hasConceptScore W2045401072C203014093 @default.
- W2045401072 hasConceptScore W2045401072C2777292125 @default.