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• W2045401426 abstract "Cannabinoid CB2 PET tracers are considered as a promising alternative to PBR/TSPO tracers for the in-vivo imaging of neuroinflammation. We describe here the synthesis and characterization of compound 3, a new potent and brain penetrating CB2 ligand based on an original triazine template. The PET tracer [18F]-dideutero-3 was prepared in a three steps radiosynthesis, and demonstrated significant uptake in rhesus macaque and baboon brain with a maximum SUV of about 0.7–0.9 g/mL, followed by a moderate washout over time." @default.
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• W2045401426 date "2014-01-01" @default.
• W2045401426 modified "2023-10-14" @default.
• W2045401426 title "Synthesis and preliminary evaluation of a new fluorine-18 labelled triazine derivative for PET imaging of cannabinoid CB2 receptor" @default.
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• W2045401426 doi "https://doi.org/10.1016/j.bmcl.2013.11.023" @default.
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