Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045443352> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2045443352 endingPage "104" @default.
- W2045443352 startingPage "95" @default.
- W2045443352 abstract "An 800-850 degrees F solvent-refined coal-II liquid was fractionated into chemical classes to obtain the aliphatic hydrocarbons, polycyclic aromatic hydrocarbons (PAH), nitrogen-containing polycyclic aromatic compounds (NPAC), and hydroxy-substituted PAH (hydroxy-PAH). The isolated NPAC fraction was refractionated by chemical class both before and after undergoing a nitrosation reaction. The nitrosated and non-nitrosated refractionated NPAC fractions were further subfractionated into secondary amine (pyrroles), primary amine-enriched (amino-PAH), and tertiary amine (azaarene) classes. The PAH and hydroxy-PAH composition of the NPAC fraction increased upon nitrosation, whereas the amino-PAH fraction composition decreased upon nitrosation. Nitrosation of standards indicated the amino-PAH compounds reacted to form parent PAH, chloro-substituted PAH, and methoxy-substituted PAH when analyzed by high-resolution gas chromatography (GC) and GC/mass spectrometry (MS). Some easily oxidized PAH compounds reacted to form ketones and quinones. All other standard reference compounds, chosen to be representative of the major chemical classes of compounds present in coal liquefaction materials, were unchanged by the nitrosation reaction. The amino-PAH of the nitrosated NPAC fraction reacted to form parent and some chloro-substituted PAH when analyzed by low-voltage direct-probe MS in addition to the methods given above. Epidermal carcinogenesis studies with the PAH, NPAC, nitrosated NPAC, and hydroxy-PAH fractions isolated from the 800-850 degrees F coal liquid indicated the PAH and NPAC were the most important determiners of skin carcinogenesis, with the PAH giving a higher response than the NPAC. The tumorigenicity of the NPAC was drastically reduced by nitrosation, probably due to the destruction of the amino-PAH upon nitrosation." @default.
- W2045443352 created "2016-06-24" @default.
- W2045443352 creator A5012002906 @default.
- W2045443352 creator A5046473814 @default.
- W2045443352 creator A5054273277 @default.
- W2045443352 creator A5079108753 @default.
- W2045443352 date "1988-04-01" @default.
- W2045443352 modified "2023-09-27" @default.
- W2045443352 title "Effects of nitrosation on the chemical composition and epidermal carcinogenicity of the nitrogen-rich fraction of a high-boiling coal liquid" @default.
- W2045443352 cites W1969035642 @default.
- W2045443352 cites W1973195696 @default.
- W2045443352 cites W1982331715 @default.
- W2045443352 cites W1991169893 @default.
- W2045443352 cites W1991927563 @default.
- W2045443352 cites W2027733855 @default.
- W2045443352 cites W2040339415 @default.
- W2045443352 cites W2071826687 @default.
- W2045443352 cites W2075350177 @default.
- W2045443352 cites W2079708060 @default.
- W2045443352 cites W2080240708 @default.
- W2045443352 cites W2082667173 @default.
- W2045443352 cites W305711558 @default.
- W2045443352 cites W4293241248 @default.
- W2045443352 doi "https://doi.org/10.1002/jat.2550080206" @default.
- W2045443352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3379237" @default.
- W2045443352 hasPublicationYear "1988" @default.
- W2045443352 type Work @default.
- W2045443352 sameAs 2045443352 @default.
- W2045443352 citedByCount "4" @default.
- W2045443352 countsByYear W20454433522012 @default.
- W2045443352 crossrefType "journal-article" @default.
- W2045443352 hasAuthorship W2045443352A5012002906 @default.
- W2045443352 hasAuthorship W2045443352A5046473814 @default.
- W2045443352 hasAuthorship W2045443352A5054273277 @default.
- W2045443352 hasAuthorship W2045443352A5079108753 @default.
- W2045443352 hasConcept C104882015 @default.
- W2045443352 hasConcept C114246631 @default.
- W2045443352 hasConcept C131779359 @default.
- W2045443352 hasConcept C149629883 @default.
- W2045443352 hasConcept C178790620 @default.
- W2045443352 hasConcept C185592680 @default.
- W2045443352 hasConcept C43617362 @default.
- W2045443352 hasConceptScore W2045443352C104882015 @default.
- W2045443352 hasConceptScore W2045443352C114246631 @default.
- W2045443352 hasConceptScore W2045443352C131779359 @default.
- W2045443352 hasConceptScore W2045443352C149629883 @default.
- W2045443352 hasConceptScore W2045443352C178790620 @default.
- W2045443352 hasConceptScore W2045443352C185592680 @default.
- W2045443352 hasConceptScore W2045443352C43617362 @default.
- W2045443352 hasIssue "2" @default.
- W2045443352 hasLocation W20454433521 @default.
- W2045443352 hasLocation W20454433522 @default.
- W2045443352 hasOpenAccess W2045443352 @default.
- W2045443352 hasPrimaryLocation W20454433521 @default.
- W2045443352 hasRelatedWork W1977572413 @default.
- W2045443352 hasRelatedWork W1987107479 @default.
- W2045443352 hasRelatedWork W2029732256 @default.
- W2045443352 hasRelatedWork W2047888616 @default.
- W2045443352 hasRelatedWork W2052675766 @default.
- W2045443352 hasRelatedWork W2084500401 @default.
- W2045443352 hasRelatedWork W2337828464 @default.
- W2045443352 hasRelatedWork W2470227202 @default.
- W2045443352 hasRelatedWork W2952281036 @default.
- W2045443352 hasRelatedWork W4312230893 @default.
- W2045443352 hasVolume "8" @default.
- W2045443352 isParatext "false" @default.
- W2045443352 isRetracted "false" @default.
- W2045443352 magId "2045443352" @default.
- W2045443352 workType "article" @default.