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- W2045446039 abstract "Bacterial genomes develop new mechanisms to tide them over the imposing conditions they encounter during the course of their evolution. Acquisition of new genes by lateral gene transfer may be one of the dominant ways of adaptation in bacterial genome evolution. Lateral gene transfer provides the bacterial genome with a new set of genes that help it to explore and adapt to new ecological niches.A maximum likelihood analysis was done on the five sequenced corynebacterial genomes to model the rates of gene insertions/deletions at various depths of the phylogeny.The study shows that most of the laterally acquired genes are transient and the inferred rates of gene movement are higher on the external branches of the phylogeny and decrease as the phylogenetic depth increases. The newly acquired genes are under relaxed selection and evolve faster than their older counterparts. Analysis of some of the functionally characterised LGTs in each species has indicated that they may have a possible adaptive role.The five Corynebacterial genomes sequenced to date have evolved by acquiring between 8-14% of their genomes by LGT and some of these genes may have a role in adaptation." @default.
- W2045446039 created "2016-06-24" @default.
- W2045446039 creator A5032060152 @default.
- W2045446039 creator A5040671482 @default.
- W2045446039 creator A5045219735 @default.
- W2045446039 date "2007-02-08" @default.
- W2045446039 modified "2023-09-27" @default.
- W2045446039 title "The role of laterally transferred genes in adaptive evolution" @default.
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