Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045451014> ?p ?o ?g. }
- W2045451014 endingPage "2881" @default.
- W2045451014 startingPage "2874" @default.
- W2045451014 abstract "Calcium phosphates have been widely used in bone and soft tissue applications and are of considerable interest as scaffold materials due to properties of osteoconduction, resorbability and in some cases osteoinduction. These materials are microcrystalline and as such are processed using sintering, surface coating or cement technologies. However calcium phosphates containing HPO(4)(2-) ions often have layered crystal structures and can form macrocrystals in an aqueous environment at room temperature and pressure. This study aimed to investigate the potential of octacalcium phosphate (OCP) crystals for the attachment, proliferation and differentiation of bone marrow stromal cells and the potential of these cell seeded crystals as 'building blocks' for manufacture of self-supporting macroscale tissue constructs. An inverse relationship between cell number and crystal surface area was found and marrow cells grown on OCP crystals expressed osteocalcin and osteopontin mRNA, markers of osteoblastic differentiation, even in the absence of inductive media additives. Self-supporting crystal tissue macroscale constructs could be fabricated by culturing cell loaded crystals in moulds of the desired shape. Due to the low packing efficiency as a consequence of the high aspect ratio of OCP crystals, this microscaffold approach may offer the potential for ex vivo construction of large volumes of tissue which forms as a physiologically vascularised tissue." @default.
- W2045451014 created "2016-06-24" @default.
- W2045451014 creator A5000333809 @default.
- W2045451014 creator A5003626240 @default.
- W2045451014 creator A5051327567 @default.
- W2045451014 creator A5071274944 @default.
- W2045451014 creator A5082274958 @default.
- W2045451014 creator A5088299148 @default.
- W2045451014 date "2006-05-01" @default.
- W2045451014 modified "2023-10-18" @default.
- W2045451014 title "Bone marrow cell gene expression and tissue construct assembly using octacalcium phosphate microscaffolds" @default.
- W2045451014 cites W1511793250 @default.
- W2045451014 cites W1574631190 @default.
- W2045451014 cites W1629179716 @default.
- W2045451014 cites W1967579581 @default.
- W2045451014 cites W1975833234 @default.
- W2045451014 cites W1978251816 @default.
- W2045451014 cites W1981504067 @default.
- W2045451014 cites W1986276800 @default.
- W2045451014 cites W1990908026 @default.
- W2045451014 cites W2000632957 @default.
- W2045451014 cites W2005720246 @default.
- W2045451014 cites W2005962739 @default.
- W2045451014 cites W2009921481 @default.
- W2045451014 cites W2015856405 @default.
- W2045451014 cites W2016811506 @default.
- W2045451014 cites W2025173639 @default.
- W2045451014 cites W2026011478 @default.
- W2045451014 cites W2028596690 @default.
- W2045451014 cites W2038969510 @default.
- W2045451014 cites W2039018534 @default.
- W2045451014 cites W2043152405 @default.
- W2045451014 cites W2045367131 @default.
- W2045451014 cites W2047971760 @default.
- W2045451014 cites W2053578740 @default.
- W2045451014 cites W2054657065 @default.
- W2045451014 cites W2055701825 @default.
- W2045451014 cites W2056969104 @default.
- W2045451014 cites W2059026308 @default.
- W2045451014 cites W2062530748 @default.
- W2045451014 cites W2068687290 @default.
- W2045451014 cites W2071032916 @default.
- W2045451014 cites W2084511789 @default.
- W2045451014 cites W2085834775 @default.
- W2045451014 cites W2086512222 @default.
- W2045451014 cites W2087609213 @default.
- W2045451014 cites W2087753698 @default.
- W2045451014 cites W2100931541 @default.
- W2045451014 cites W2104176186 @default.
- W2045451014 cites W2106121106 @default.
- W2045451014 cites W2107603161 @default.
- W2045451014 cites W2107649335 @default.
- W2045451014 cites W2127066215 @default.
- W2045451014 cites W2141425377 @default.
- W2045451014 cites W4252936428 @default.
- W2045451014 cites W5780337 @default.
- W2045451014 doi "https://doi.org/10.1016/j.biomaterials.2005.12.031" @default.
- W2045451014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16439012" @default.
- W2045451014 hasPublicationYear "2006" @default.
- W2045451014 type Work @default.
- W2045451014 sameAs 2045451014 @default.
- W2045451014 citedByCount "94" @default.
- W2045451014 countsByYear W20454510142012 @default.
- W2045451014 countsByYear W20454510142013 @default.
- W2045451014 countsByYear W20454510142014 @default.
- W2045451014 countsByYear W20454510142015 @default.
- W2045451014 countsByYear W20454510142016 @default.
- W2045451014 countsByYear W20454510142017 @default.
- W2045451014 countsByYear W20454510142018 @default.
- W2045451014 countsByYear W20454510142019 @default.
- W2045451014 countsByYear W20454510142020 @default.
- W2045451014 countsByYear W20454510142021 @default.
- W2045451014 countsByYear W20454510142022 @default.
- W2045451014 countsByYear W20454510142023 @default.
- W2045451014 crossrefType "journal-article" @default.
- W2045451014 hasAuthorship W2045451014A5000333809 @default.
- W2045451014 hasAuthorship W2045451014A5003626240 @default.
- W2045451014 hasAuthorship W2045451014A5051327567 @default.
- W2045451014 hasAuthorship W2045451014A5071274944 @default.
- W2045451014 hasAuthorship W2045451014A5082274958 @default.
- W2045451014 hasAuthorship W2045451014A5088299148 @default.
- W2045451014 hasConcept C104169306 @default.
- W2045451014 hasConcept C12554922 @default.
- W2045451014 hasConcept C131075544 @default.
- W2045451014 hasConcept C136229726 @default.
- W2045451014 hasConcept C160160445 @default.
- W2045451014 hasConcept C16930146 @default.
- W2045451014 hasConcept C181199279 @default.
- W2045451014 hasConcept C185592680 @default.
- W2045451014 hasConcept C191897082 @default.
- W2045451014 hasConcept C192562407 @default.
- W2045451014 hasConcept C201370411 @default.
- W2045451014 hasConcept C203014093 @default.
- W2045451014 hasConcept C2775971857 @default.
- W2045451014 hasConcept C2778606738 @default.
- W2045451014 hasConcept C2780804394 @default.
- W2045451014 hasConcept C502942594 @default.
- W2045451014 hasConcept C519063684 @default.