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- W2045451799 startingPage "1267" @default.
- W2045451799 abstract "Cell division, in addition to an accurate transmission of genetic information to daughter cells, also requires the temporal and spatial coordination of several biological processes without which cell division would not be feasible. These processes include the temporal coordination of DNA replication and chromosome segregation, regulation of nuclear envelope disassembly and assembly, chromatin condensation and Golgi fragmentation for its redistribution into daughter cells, among others. However, little is known regarding regulatory proteins and signalling pathways that might participate in the coordination of all these different biological functions. Such regulatory players should directly have a role in the processes leading to cell division. VRK1 (Vaccinia-related kinase 1) is an early response gene required for cyclin D1 expression, regulates p53 by a specific Thr18 phosphorylation, controls chromatin condensation by histone phosphorylation, nuclear envelope assembly by phosphorylation of BANF1, and participates in signalling required for Golgi fragmentation late in the G2 phase. We propose that VRK1, a Ser–Thr kinase, might be a candidate to play an important coordinator role in these cell division processes as part of a novel signalling pathway." @default.
- W2045451799 created "2016-06-24" @default.
- W2045451799 creator A5005498435 @default.
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- W2045451799 creator A5011280844 @default.
- W2045451799 creator A5061071386 @default.
- W2045451799 creator A5077292020 @default.
- W2045451799 date "2011-08-01" @default.
- W2045451799 modified "2023-10-02" @default.
- W2045451799 title "Roles of VRK1 as a new player in the control of biological processes required for cell division" @default.
- W2045451799 cites W1518840648 @default.
- W2045451799 cites W1596753747 @default.
- W2045451799 cites W1606409542 @default.
- W2045451799 cites W1964719993 @default.
- W2045451799 cites W1965965755 @default.
- W2045451799 cites W1967289736 @default.
- W2045451799 cites W1967880683 @default.
- W2045451799 cites W1975760108 @default.
- W2045451799 cites W1976261939 @default.
- W2045451799 cites W1978425667 @default.
- W2045451799 cites W1980915249 @default.
- W2045451799 cites W1991690400 @default.
- W2045451799 cites W1992336935 @default.
- W2045451799 cites W1994844856 @default.
- W2045451799 cites W2002890978 @default.
- W2045451799 cites W2004241887 @default.
- W2045451799 cites W2004813514 @default.
- W2045451799 cites W2006401070 @default.
- W2045451799 cites W2007391357 @default.
- W2045451799 cites W2008933923 @default.
- W2045451799 cites W2014294449 @default.
- W2045451799 cites W2014977510 @default.
- W2045451799 cites W2015306588 @default.
- W2045451799 cites W2015943575 @default.
- W2045451799 cites W2016619116 @default.
- W2045451799 cites W2017345097 @default.
- W2045451799 cites W2019940112 @default.
- W2045451799 cites W2022064228 @default.
- W2045451799 cites W2023568503 @default.
- W2045451799 cites W2025476423 @default.
- W2045451799 cites W2029883898 @default.
- W2045451799 cites W2030205108 @default.
- W2045451799 cites W2032580087 @default.
- W2045451799 cites W2039572110 @default.
- W2045451799 cites W2040331457 @default.
- W2045451799 cites W2043886539 @default.
- W2045451799 cites W2050686338 @default.
- W2045451799 cites W2054208935 @default.
- W2045451799 cites W2056132322 @default.
- W2045451799 cites W2057524151 @default.
- W2045451799 cites W2058947924 @default.
- W2045451799 cites W2059521716 @default.
- W2045451799 cites W2059642730 @default.
- W2045451799 cites W2063954717 @default.
- W2045451799 cites W2068371312 @default.
- W2045451799 cites W2071822958 @default.
- W2045451799 cites W2077422245 @default.
- W2045451799 cites W2077804275 @default.
- W2045451799 cites W2079007120 @default.
- W2045451799 cites W2080244557 @default.
- W2045451799 cites W2082765852 @default.
- W2045451799 cites W2083146650 @default.
- W2045451799 cites W2083259022 @default.
- W2045451799 cites W2086880316 @default.
- W2045451799 cites W2097651998 @default.
- W2045451799 cites W2100772783 @default.
- W2045451799 cites W2103176226 @default.
- W2045451799 cites W2104076764 @default.
- W2045451799 cites W2106942695 @default.
- W2045451799 cites W2114626430 @default.
- W2045451799 cites W2117692326 @default.
- W2045451799 cites W2118733942 @default.
- W2045451799 cites W2123879591 @default.
- W2045451799 cites W2124498519 @default.
- W2045451799 cites W2128121763 @default.
- W2045451799 cites W2130043237 @default.
- W2045451799 cites W2131559143 @default.
- W2045451799 cites W2133532796 @default.
- W2045451799 cites W2135458195 @default.
- W2045451799 cites W2139596383 @default.
- W2045451799 cites W2139728867 @default.
- W2045451799 cites W2140844543 @default.
- W2045451799 cites W2145877883 @default.
- W2045451799 cites W2146092038 @default.
- W2045451799 cites W2148399857 @default.
- W2045451799 cites W2150027419 @default.
- W2045451799 cites W2152907403 @default.
- W2045451799 cites W2153998010 @default.
- W2045451799 cites W2154841454 @default.
- W2045451799 cites W2157615753 @default.
- W2045451799 cites W2158132053 @default.
- W2045451799 cites W2162426125 @default.
- W2045451799 cites W2164785233 @default.
- W2045451799 cites W2170520206 @default.
- W2045451799 cites W3044475 @default.
- W2045451799 doi "https://doi.org/10.1016/j.cellsig.2011.04.002" @default.
- W2045451799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21514377" @default.
- W2045451799 hasPublicationYear "2011" @default.