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• W2045452530 startingPage "65" @default.
• W2045452530 abstract "<i>Aims:</i> To evaluate midtrimester amniotic fluid leptin levels in pregnancies subsequently complicated by gestational diabetes. <i>Methods:</i> We studied 32 pregnant women with gestational diabetes and a control group of 43 normal pregnancies with an adequate gestational age fetus. All underwent a midtrimester amniocentesis: leptin and insulin were measured in the amniotic fluid. Data were compared with the Mann-Whitney U-test. <i>Results:</i> Median leptin concentrations in the amniotic fluid of the gestational diabetes mellitus patients were significantly higher than in the control group (15.1 vs. 7.9 ng/ml) (p = 0.001); amniotic insulin concentrations were also higher in the gestational diabetes mellitus than in the control group (0.67 vs. 0.38 µU/ml) (p = 0.02). Furthermore, amniotic fluid leptin levels were directly correlated with amniotic insulin concentrations; instead, there was no correlation with maternal BMI and birth weight. <i>Conclusion:</i> Our data suggest that in pregnancies subsequently complicated by gestational diabetes, amniotic fluid leptin and insulin levels are higher in the early fetal period." @default.
• W2045452530 created "2016-06-24" @default.
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• W2045452530 date "2007-01-01" @default.
• W2045452530 modified "2023-10-18" @default.
• W2045452530 title "Midtrimester Amniotic Fluid Leptin and Insulin Levels and Subsequent Gestational Diabetes" @default.
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• W2045452530 doi "https://doi.org/10.1159/000099149" @default.
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