FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045463977> ?p ?o ?g. }

• W2045463977 endingPage "70" @default.
• W2045463977 startingPage "64" @default.
• W2045463977 abstract "Recent epidemiological studies have indicated numerous associations between vascular and lifestyle related risk factors and incident dementia. However, evidence from randomised controlled trials (RCT) showing effectiveness of interventions aimed at these risk factors in preventing or postponing dementia onset is still lacking. Three large RCTs on multi-component interventions to prevent dementia (preDIVA, FINGER, MAPT) have been initiated in Europe to address these issues. Irrespective of some methodological differences, all three studies target cardiovascular and lifestyle related risk factors. Collaboration within the newly founded 'European Dementia Prevention Initiative' (EDPI) will allow for a comprehensive exploration of optimal target population, intervention and outcome measures, which are currently unknown. Combining data of the ongoing studies and running simulation analyses will facilitate determining the optimal design including accurate sample-size calculations for future multi-national clinical trials on dementia prevention. Interventions aiming at dementia prevention should be pragmatic and easy to implement on a large scale in different health care systems, without generating high additional costs or burden on participants or physicians. As the optimal age for intervention precedes the optimal age for outcome assessment, traditional trial designs might lead to suboptimal timing of either of the two. Separation of intervention and outcome assessment in time is a potential solution, but requires studies with very long follow-up. International collaboration of research groups with experience in dementia prevention studies and well-organised logistics for these major projects is pivotal to success for future large-scale dementia prevention studies. Founding of EDPI is an important first step in this direction." @default.
• W2045463977 created "2016-06-24" @default.
• W2045463977 creator A5003551986 @default.
• W2045463977 creator A5016653962 @default.
• W2045463977 creator A5029660613 @default.
• W2045463977 creator A5031617464 @default.
• W2045463977 creator A5033714718 @default.
• W2045463977 creator A5039682168 @default.
• W2045463977 creator A5047149331 @default.
• W2045463977 creator A5049484291 @default.
• W2045463977 creator A5061339701 @default.
• W2045463977 creator A5068519823 @default.
• W2045463977 creator A5086456642 @default.
• W2045463977 creator A5091014178 @default.
• W2045463977 date "2012-11-01" @default.
• W2045463977 modified "2023-09-25" @default.
• W2045463977 title "Methodological challenges in designing dementia prevention trials — The European Dementia Prevention Initiative (EDPI)" @default.
• W2045463977 cites W1493334241 @default.
• W2045463977 cites W1531301069 @default.
• W2045463977 cites W1573095991 @default.
• W2045463977 cites W1586213696 @default.
• W2045463977 cites W1608072969 @default.
• W2045463977 cites W1847168837 @default.
• W2045463977 cites W1963973361 @default.
• W2045463977 cites W1964268352 @default.
• W2045463977 cites W1980542913 @default.
• W2045463977 cites W1983349802 @default.
• W2045463977 cites W1983875962 @default.
• W2045463977 cites W1989104104 @default.
• W2045463977 cites W1990012771 @default.
• W2045463977 cites W1992723640 @default.
• W2045463977 cites W1998088268 @default.
• W2045463977 cites W2007316570 @default.
• W2045463977 cites W2009869050 @default.
• W2045463977 cites W2012469800 @default.
• W2045463977 cites W2014886338 @default.
• W2045463977 cites W2016865804 @default.
• W2045463977 cites W2028436804 @default.
• W2045463977 cites W2034897558 @default.
• W2045463977 cites W2040056856 @default.
• W2045463977 cites W2043115154 @default.
• W2045463977 cites W2044864416 @default.
• W2045463977 cites W2047770228 @default.
• W2045463977 cites W2057042201 @default.
• W2045463977 cites W2076467171 @default.
• W2045463977 cites W2076688918 @default.
• W2045463977 cites W2077468399 @default.
• W2045463977 cites W2080503418 @default.
• W2045463977 cites W2085179244 @default.
• W2045463977 cites W2088780441 @default.
• W2045463977 cites W2092909353 @default.
• W2045463977 cites W2097744656 @default.
• W2045463977 cites W2098706789 @default.
• W2045463977 cites W2100464372 @default.
• W2045463977 cites W2100582650 @default.
• W2045463977 cites W2101584773 @default.
• W2045463977 cites W2102528806 @default.
• W2045463977 cites W2104565625 @default.
• W2045463977 cites W2105489250 @default.
• W2045463977 cites W2106159603 @default.
• W2045463977 cites W2110364190 @default.
• W2045463977 cites W2117567858 @default.
• W2045463977 cites W2122320288 @default.
• W2045463977 cites W2124681501 @default.
• W2045463977 cites W2124956656 @default.
• W2045463977 cites W2126579393 @default.
• W2045463977 cites W2130052234 @default.
• W2045463977 cites W2131162932 @default.
• W2045463977 cites W2132666355 @default.
• W2045463977 cites W2135631433 @default.
• W2045463977 cites W2136057401 @default.
• W2045463977 cites W2136520115 @default.
• W2045463977 cites W2136953651 @default.
• W2045463977 cites W2146392529 @default.
• W2045463977 cites W2149486086 @default.
• W2045463977 cites W2152532350 @default.
• W2045463977 cites W2153415741 @default.
• W2045463977 cites W2155537822 @default.
• W2045463977 cites W2160643135 @default.
• W2045463977 cites W2165146299 @default.
• W2045463977 cites W2165828128 @default.
• W2045463977 cites W2332951586 @default.
• W2045463977 cites W424467158 @default.
• W2045463977 doi "https://doi.org/10.1016/j.jns.2012.06.012" @default.
• W2045463977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22818266" @default.
• W2045463977 hasPublicationYear "2012" @default.
• W2045463977 type Work @default.
• W2045463977 sameAs 2045463977 @default.
• W2045463977 citedByCount "96" @default.
• W2045463977 countsByYear W20454639772012 @default.
• W2045463977 countsByYear W20454639772013 @default.
• W2045463977 countsByYear W20454639772014 @default.
• W2045463977 countsByYear W20454639772015 @default.
• W2045463977 countsByYear W20454639772016 @default.
• W2045463977 countsByYear W20454639772017 @default.
• W2045463977 countsByYear W20454639772018 @default.
• W2045463977 countsByYear W20454639772019 @default.
• W2045463977 countsByYear W20454639772020 @default.

• next