FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045467046> ?p ?o ?g. }

• W2045467046 endingPage "379" @default.
• W2045467046 startingPage "379" @default.
• W2045467046 abstract "Leishmania infantum and Leishmania donovani both pertain to the L. (L.) donovani complex and are responsible for visceral leishmaniasis. To explore the L. donovani complex, we focused our study on cysteine protease B (cpb) and especially on 2 cpb copies: cpbE and cpbF. We selected cpb genes because of their phylogenetic interest and host–parasite interaction involvement. Sequencing these 2 copies revealed (i) that cpbE is specific to L. infantum and cpbF is specific to L. donovani and (ii) that these 2 copies are different in length and sequence.Nucleotide sequence data reported in this paper are available in the GenBank database under Accession numbers AY896776 AY896777, AY896778, AY896779, AY896780, AY896781, AY896782, AY896783, AY896784, AY896785, AY896786, AY896787, AY896788, AY896789, AY896790, AY896791. Phylogenetic analysis and protein predictions were carried out in order to compare these copies (i) with other trypanosomatid cpb, especially L. mexicana, and (ii) within the L. donovani complex. Our results revealed patterns specific to the L. donovani complex such as the COOH-terminal extension, potential epitopes and N-glycosylation sites. Moreover, phylogenetic analysis revealed different levels of polymorphism between L. infantum and L. donovani and confirmed the ancestral status of the latter. L. infantum has a shorter sequence and a deleted sequence responsible for modifications in protein conformation and catalytic triad. Considering the clinical aspect, L. infantum dermotropic strains appeared more polymorphic than L. infantum viscerotropic strains." @default.
• W2045467046 created "2016-06-24" @default.
• W2045467046 creator A5027768319 @default.
• W2045467046 creator A5068827445 @default.
• W2045467046 creator A5084051743 @default.
• W2045467046 date "2006-11-28" @default.
• W2045467046 modified "2023-10-18" @default.
• W2045467046 title "Specific cpb copies within the Leishmania donovani complex: evolutionary interpretations and potential clinical implications in humans" @default.
• W2045467046 cites W1906772957 @default.
• W2045467046 cites W1965526161 @default.
• W2045467046 cites W1979818665 @default.
• W2045467046 cites W1987238446 @default.
• W2045467046 cites W1993061124 @default.
• W2045467046 cites W1997034856 @default.
• W2045467046 cites W2002204067 @default.
• W2045467046 cites W2009972285 @default.
• W2045467046 cites W2012183067 @default.
• W2045467046 cites W2021556766 @default.
• W2045467046 cites W2024373248 @default.
• W2045467046 cites W2033057312 @default.
• W2045467046 cites W2034433507 @default.
• W2045467046 cites W2051476262 @default.
• W2045467046 cites W2053312115 @default.
• W2045467046 cites W2065461553 @default.
• W2045467046 cites W2065701763 @default.
• W2045467046 cites W2074752318 @default.
• W2045467046 cites W2076375813 @default.
• W2045467046 cites W2088245563 @default.
• W2045467046 cites W2097382368 @default.
• W2045467046 cites W2102424972 @default.
• W2045467046 cites W2106872016 @default.
• W2045467046 cites W2114282783 @default.
• W2045467046 cites W2115650522 @default.
• W2045467046 cites W2122683207 @default.
• W2045467046 cites W2132360440 @default.
• W2045467046 cites W2165187963 @default.
• W2045467046 cites W2168797800 @default.
• W2045467046 cites W2171388951 @default.
• W2045467046 cites W4245589101 @default.
• W2045467046 doi "https://doi.org/10.1017/s0031182006001600" @default.
• W2045467046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17129395" @default.
• W2045467046 hasPublicationYear "2006" @default.
• W2045467046 type Work @default.
• W2045467046 sameAs 2045467046 @default.
• W2045467046 citedByCount "30" @default.
• W2045467046 countsByYear W20454670462012 @default.
• W2045467046 countsByYear W20454670462013 @default.
• W2045467046 countsByYear W20454670462014 @default.
• W2045467046 countsByYear W20454670462015 @default.
• W2045467046 countsByYear W20454670462016 @default.
• W2045467046 countsByYear W20454670462017 @default.
• W2045467046 countsByYear W20454670462018 @default.
• W2045467046 countsByYear W20454670462019 @default.
• W2045467046 countsByYear W20454670462020 @default.
• W2045467046 countsByYear W20454670462021 @default.
• W2045467046 countsByYear W20454670462022 @default.
• W2045467046 crossrefType "journal-article" @default.
• W2045467046 hasAuthorship W2045467046A5027768319 @default.
• W2045467046 hasAuthorship W2045467046A5068827445 @default.
• W2045467046 hasAuthorship W2045467046A5084051743 @default.
• W2045467046 hasConcept C104317684 @default.
• W2045467046 hasConcept C193252679 @default.
• W2045467046 hasConcept C2776555147 @default.
• W2045467046 hasConcept C2778689377 @default.
• W2045467046 hasConcept C2781257258 @default.
• W2045467046 hasConcept C2781333301 @default.
• W2045467046 hasConcept C54355233 @default.
• W2045467046 hasConcept C79029880 @default.
• W2045467046 hasConcept C86803240 @default.
• W2045467046 hasConceptScore W2045467046C104317684 @default.
• W2045467046 hasConceptScore W2045467046C193252679 @default.
• W2045467046 hasConceptScore W2045467046C2776555147 @default.
• W2045467046 hasConceptScore W2045467046C2778689377 @default.
• W2045467046 hasConceptScore W2045467046C2781257258 @default.
• W2045467046 hasConceptScore W2045467046C2781333301 @default.
• W2045467046 hasConceptScore W2045467046C54355233 @default.
• W2045467046 hasConceptScore W2045467046C79029880 @default.
• W2045467046 hasConceptScore W2045467046C86803240 @default.
• W2045467046 hasIssue "03" @default.
• W2045467046 hasLocation W20454670461 @default.
• W2045467046 hasLocation W20454670462 @default.
• W2045467046 hasLocation W20454670463 @default.
• W2045467046 hasOpenAccess W2045467046 @default.
• W2045467046 hasPrimaryLocation W20454670461 @default.
• W2045467046 hasRelatedWork W1523879710 @default.
• W2045467046 hasRelatedWork W2045467046 @default.
• W2045467046 hasRelatedWork W2135809436 @default.
• W2045467046 hasRelatedWork W2178924032 @default.
• W2045467046 hasRelatedWork W2332253995 @default.
• W2045467046 hasRelatedWork W2461948648 @default.
• W2045467046 hasRelatedWork W2917115993 @default.
• W2045467046 hasRelatedWork W3015699985 @default.
• W2045467046 hasRelatedWork W4210690519 @default.
• W2045467046 hasRelatedWork W4225552864 @default.
• W2045467046 hasVolume "134" @default.
• W2045467046 isParatext "false" @default.
• W2045467046 isRetracted "false" @default.
• W2045467046 magId "2045467046" @default.

• next