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- W2045471963 abstract "ATP-dependent Cl- uptake by membrane vesicles from the rat brain plasma membrane fractions was not affected by the addition of 40 mM of K+, Na+ or HCO3- to the assay medium. Na+ and K+ did not alter the uptake even in the presence of a K+ ionophore, valinomycin (10 microM), or a H+/K+ exchanger, nigericin (10 microM), whereas in the presence of both of these ionophores, K+, but not Na+, reduced the Cl- uptake. Inhibitors of proton pump activity, N,N'-dicyclohexylcarbodiimide (1 mM) and 5-(N,N-hexamethylene)amiloride (40 microM), however, did not affect the Cl- uptake. These findings suggest the presence of a primary Cl- transport system probably associated with passive H+ flux in the brain plasma membranes." @default.
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- W2045471963 date "1989-04-01" @default.
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- W2045471963 title "ATP-dependent and DCCD-insensitive Cl− uptake by membrane vesicles from the rat brain plasma membrane fractions" @default.
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- W2045471963 doi "https://doi.org/10.1016/0006-291x(89)92456-x" @default.
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