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• W2045472172 abstract "<h3>Objective</h3> The contribution of sexual transmission to genital <i>Candida</i> infection remains unclear. This study sought to investigate whether sexual behaviours were associated with the presence of genital <i>Candida</i> species among a cohort of women who have sex with women (WSW) in addition to determining the genetic concordance of genital <i>Candida</i> spp. among WSW in sexual partnerships. <h3>Methods</h3> WSW ≥18 years of age presenting to the Mississippi State Department of Health STD Clinic during 2009–2010 completed a sexual behaviour survey. Culture of vaginal fluid was performed for <i>Candida</i> spp. identification; associations with participant characteristics were determined using logistic regression analysis. Random amplified polymorphic DNA (RAPD) PCR was performed on DNA extracted from yeast cultures of WSW in sexual partnerships in which both partners had isolates of <i>Candida</i> spp. identified and among a set of age/sexual behaviour matched controls. RAPD genetic fingerprints were evaluated by hierarchical cluster analysis for concordance. <h3>Results</h3> Genital <i>Candida</i> spp. were isolated in 105/196 (53.6%) of women: 13/105 (12.4%) had symptomatic vulvovaginal candidiasis while 92/105 (87.6%) had asymptomatic vaginal colonisation. Bisexual identity, sex with women and men during the past 12 months and numbers of male sexual partners during the past 12 months were the only significant predictors of genital <i>Candida</i> spp. in bivariate analysis. 13 pairs of WSW in sexual partnerships in which both partners had genital <i>Candida</i> spp. and 11 WSW with genital <i>Candida</i> spp. not in sexual partnerships were identified. <i>Candida</i> spp. RAPD banding patterns were discordant for all isolates among WSW within partnerships and in controls. <h3>Conclusions</h3> This study found no evidence supporting sexual transmission of genital <i>Candida</i> spp. between women." @default.
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• W2045472172 date "2014-01-15" @default.
• W2045472172 modified "2023-10-01" @default.
• W2045472172 title "Lack of evidence for sexual transmission of genitalCandidaspecies among women who have sex with women: a mixed methods study" @default.
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• W2045472172 doi "https://doi.org/10.1136/sextrans-2013-051361" @default.
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